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논문 기본 정보

자료유형
학술저널
저자정보
김미혜 (연세대학교 의과대학 진단방사선과학교실)
저널정보
대한영상의학회 대한방사선의학회지 대한방사선의학회지 제32권 제2호
발행연도
1995.1
수록면
331 - 336 (6page)

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Purpose:To evaluate differential points of clustered microcalcification in malignant and benign lesions onhistopathology and correlate with mammographic findings. Materials and Methods: Authors evaluated differentialpoints of malignant and benign calcificaitons in histopathologically confirmed 24 cases. In two patients, mappingstudies and paraffin block mammographic examinations were done to correlate calcification on mammography withhistopathologic morphology. Result: On histopathology, malignant calcifications were located in ductal lumen,while benign ones were usually located in ductal epithelium(p<0.05). However, associated three benign lesions ofthe 10 malignant lesions showed still benign calcifications adjacent to proven cancer. The typical malignantcalcifications were the shape of lamination, while benign calcifications showed granular and salty on lightmicroscope.In 2 mapping studies, malignant-looking calcifications within the area of predominant benigncalcifications yielded atypical ductal hyperplasia. Mammographic pepper,granular, punctate, salty and S-shapedcalcifications were correlated with granular and salty calcification on light microscope. Mammographic linear,branching, comma, tadpole and wormiform calcifications were correlated with histopathologic laminatedcalcification. Conclusion: Authors have recognized about characteristics of malignant Vs. benign clusteredmicrocalcifications on histopathology. Authors concluded that if malignant-looking calcification such as linear,branching, comma, tadpole and wormiform are present in an are a of predominant benign calcifications, specimenradiographic correlation and mapping study will be necessary for better demonstration of the atypical ductalhyperplasia, hidden or associated breast cancer.

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