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논문 기본 정보

자료유형
학술저널
저자정보
Ku, Sae-Kwang (Pharmacol & Toxicology Laboratory, Central Research Laboratories, Dong-Wha Pharmacetucal Industry Co) Lee, Hyeung-Sik (Department of Biology, Faculty of Natural Sciences, Kyungsan University) Park, Ki-Dae (Laboratory of Histology, College of Veterinary Medicine, Kyungpook National University) Lee, Jae-Hyun (Department of Biology, Faculty of Natural Sciences, Kyungsan University)
저널정보
한국통합생물학회 Korean journal of biological sciences Korean journal of biological sciences 제4권 제4호
발행연도
2000.1
수록면
375 - 379 (5page)

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초록· 키워드

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The appearance of some gastrointestinal endocrine cells in the Meckel's diverticulum (MD) of the bean goose, Anser fabalis Latham was observed using specific antisera against serotonin, gastrin, cholecystokinin (CCK)-8, glucagon, secretin, somatostatin and human pancreatic polypeptide (HPP) with the peroxidase antiperoxidase (PAP) method. Among these specific antisera, serotonin-, gastrin-, CCK-8-, somatostatin- and HPP-immunoreactive cells were demonstrated in this study. Serotonin-, gastrin- and somatostatin-immunoreactive cells were detected at moderate frequency and CCK-8- and HPP-immunoreactive cells was rare and low frequencies, respectively. These immunoreactive cells were located in the superficial epithelium, intestinal crvpt and intestinal glands with spherical or spindle shaped cells having long cytoplasmic processes (open typed-cell). Mucosal layer of MD was composed of simple columnar epithelium and numerous intestinal glands. In addition, numerous lymphatic tissues were also demonstrated. In conclusion, histological profiles of MD were similar to any parts of the large intestine, especially the cecum, but the appearance, distribution and relative frequency of gastrointestinal endocrine cells were similar to those of upper parts of the small intestine. Although the exact digestive functions were unknown, the finding that the appearance, distribution and relative frequency of gastrointestinal endocrine cells in MD is similar to small intestine may be considered as distinct evidence that this organ may have some digestive functions.

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