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자료유형
학술저널
저자정보
Hannan, JMA (Department of Pharmacology, Research Division, BIRDEM) Shahriar, Masum (Department of Pharmacy, Gono Bishwabidyalay) Islam, M Naimul (Ethnopharmacology Laboratory, Department of Pharmacy, Jahangirnagar University) Sattar, Mafruhi (Ethnopharmacology Laboratory, Department of Pharmacy, Jahangirnagar University) Haque, Sabera (Ethnopharmacology Laboratory, Department of Pharmacy, Jahangirnagar University) Choudhuri, MSK (Ethnopharmacology Laboratory, Department of Pharmacy, Jahangirnagar University)
저널정보
경희한의학연구센터 Oriental pharmacy and experimental medicine Oriental pharmacy and experimental medicine 제3권 제1호
발행연도
2003.1
수록면
8 - 17 (10page)

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Water extract (kwath) of six different widely used Ayurvedic medicinal plants were tested in mice for possible neuropharmacological efficacy. In the present experiments it was observed that a number of plant tested causes a significant level of Central Nervous System (CNS) depression, in that it significantly decreased the spontaneous Motor activity, and also lowered the exploratory behavior of the treated animals. Terminalia chebula (HAA), Terminalia bellerica (BHA), Emblica officinalis (AA), Piper longum 1. (PP). exhibited depressant action of on the CNS. Apart from them a mild to moderate degree of depression was evident as a consequence of administration of Zingiber officinale Rosc (SUT), Piper nigrum L. (MRC). However, none of the plant tested did not exhibit significant effects on pentobarbital induced narcosis, and this indicated that the sedating effects of the drug was not associated with the risk of fatal consequences on overdose.

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