지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국응용약물학회 The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology 제11권 제3호
- 발행연도
- 2003.1
- 수록면
- 190 - 195 (6page)
이용수
초록· 키워드
오류제보하기
To assess the genotoxicity of AS6, several classical toxicological tests were performed. In Ames test, AS6 did not show any transformation of revertant with or without S-9 metabolic activating system, indicating the lack of mutagenic effect of the compound. To assess clastogenic effect, in vivo micronucleus and in vitro chromosomal aberration assays were performed using male ICR mice and Chinese hamster lung (CHL) fibroblast cells, respectively. Chromosomal aberration was not induced regardless of the presence of S-9 metabolic activating system. In addition, AS6 did not cause any increase in the incidence of micronucleated polychromatic erythrocytes at any of the dose levels, suggesting little clastogenicity in vitro or in vivo. Taken together, these results demonstrate that AS-6 has no mutagenic effect in our test system.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Genotoxicity Studies on Carrageenan : Short-term In Vitro Assays
Toxicological Research
2009 .03
-
Genotoxicity Test on 3,9-Diferuloyl-6-oxopterocarpen, a New Agent Candidate for Anti-aging Material
Laboratory Animal Research
2008 .03
-
Genotoxicity Assessment of Erythritol by Using Short-term Assay
Toxicological Research
2013 .12
-
In Vitro Studies on the Genotoxic Effects of Wood Smoke Flavors
Toxicological Research
2008 .12
-
Evaluation of Genotoxicity of Water and Ethanol Extracts from Rhus verniciflua Stokes (RVS)
Toxicological Research
2008 .06
-
In Vitro Genotoxicity Assessment of a Novel Resveratrol Analogue, HS-1793
Toxicological Research
2014 .09
-
Evaluation of the genetic toxicity of synthetic chemicals (Ⅴ) - in vitro Chromosomal Aberration Assay with 17 chemicals in Chinese Hamster Lung Cells -
한국환경성돌연변이·발암원학회지
2002 .12
-
Acriflavine과 Guanosine 복합체(AG60)의 유전독성시험
한국환경성돌연변이·발암원학회지
2002 .06
-
Evaluation of the Genetic Toxicity of Synthetic Chemicals (XIV)-in vitro Chromosomal Aberration Assay with 11 Chemicals in Chinese Hamster Lung Cells
Molecular & cellular toxicology
2006 .01
-
Studies on the Genetic Toxicity of NP-77A
한국응용약물학회 춘계학술발표논문집
1995 .01
-
Genotoxicity of Recombinant Human Basic Fibroblast Growth Factor
Toxicological Research
1999 .09
-
GST 추출물의 유전독성평가
동의생리병리학회지
2014 .12
-
CJ-11555의 유전독성에 관한 연구
Toxicological Research
2004 .06
-
CJ-11555의 유전독성에 관한 연구
Toxicological Research
2004 .03
-
Evaluation of the Genetic Toxicity of Synthetic Chemicals (Ⅳ) - in vitro Chromosomal Aberration Assay with 18 Chemicals in Chinese Hamster Lung Cells -
한국환경성돌연변이·발암원학회지
2002 .09
-
염색체이상을 의심한 1,180례의 염색체 분석 결과 검토
Clinical and Experimental Pediatrics
2002 .01
-
Evaluation of the Genetic Toxicity of Synthetic Chemicals (XII) - in vitro Chromosomal Aberration Assay with 11 Chemicals in Chinese Hamster Lung Fibroblast -
한국환경성돌연변이·발암원학회지
2004 .06
-
Evaluation of the Genetic Toxicity of Synthetic Chemicals (Ⅲ) - in vitro Chromosomal Aberration Assay with 28 Chemicals in Chinese Hamster Lung Cells -
한국환경성돌연변이·발암원학회지
2001 .03
-
Genotoxicity Assessment of Gardenia Yellow using Short-term Assays
Molecular & cellular toxicology
2009 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0