지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 경희한의학연구센터 Oriental pharmacy and experimental medicine Oriental pharmacy and experimental medicine 제6권 제3호
- 발행연도
- 2006.1
- 수록면
- 237 - 244 (8page)
이용수
초록· 키워드
오류제보하기
Samultang has been believed for prevention and remedy various blood diseases such as menstrual irregularity, anemia, and metrorrhagia. However, the mechanism that accounts for anti-inflammatory effects of the Samultang is still not fully understood. This study was designed to evaluate whether and how the Samultang could modulate the production of pro-inflammatory cytokines in phorbol 12-myristate 13-acetate (PMA) plus calcium ionophore A23187 treated-human mast cell line, HMC-1. Samultang inhibited the production of tumor necrosis factor $(TNF)-\alpha$, interleukin (IL)-6, granulocyte macrophage colony stimulating factor (GM-CSF), and vascular endothelial growth factor (VEGF) in HMC-1. Maximal inhibition rate of $TNF-\alpha$, IL-6, GM-CSF, and VEGF by 0.1 mg/ml Samultang was about $70.73{\pm}3.0%,\;51.49{\pm}4.14%,\;54.03{\pm}2.09%$, and $47.95{\pm}7.86%$, respectively. Samultang partially blocked PMA plus A23187-induced cyclooxygenase (COX)-2 expression. In addition, Samultang inhibited activation of nuclear factor (NF)-kB, and extracellular signal-regulated kinase (ERK) activation. These results suggest that anti-inflammatory effect of Samulatng may be mediated by the suppression of cytokine production and COX-2 activation via down-regulation of NF-kB and ERK activation.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
사군자탕(四君子湯)과 사물탕(四物湯)의 효능에 관한 연구경향 분석
논문집 : 대전대학교 한의학연구소. 한의학편
2011 .01
-
Effects of Samultang on Immune Function during the late stage of Pregnancy in Mice
대한약학회 학술대회
2000 .01
-
Typha orientalis inhibits inflammatory cytokine expression through suppression of ERK phosphorylation in HMC-1 cells
Oriental pharmacy and experimental medicine
2010 .01
-
Effect of Korean folk medicine 'SecSec' on inflammatory cytokine secretion in HMC-1 cells
Oriental pharmacy and experimental medicine
2005 .01
-
Panax Ginseng inhibited HIF-1a activation and inflammatory cytokine in HMC-1 cells activated by phorbol myristate acetate and A23187
Oriental pharmacy and experimental medicine
2008 .01
-
사물탕(四物湯)과 사물탕(四物湯) 구성약물(構成藥物)이 혈구감소증(血球減少症)에 미치는 영향(影響)에 관(關)한 연구(硏究)
논문집 : 대전대학교 한의학연구소. 한의학편
1999 .01
-
인간 비만세포에서 PMA와 A23187에 의해 유도된 전염증 매개체에 대한 신효월도산 추출물의 항염증 효과
대한본초학회지(본초분과학회지)
2014 .01
-
Regulatory Effect of Inflammatory Cytokines Secretion and Hypoxia-inducible Factor-1α Activation by Panax ginseng
대한한방내과학회지
2006 .01
-
승마갈근탕(升麻葛根湯) 및 승마갈근탕합사물탕(升麻葛根湯合四物湯)의 항(抗) Histamine 효과(效果)에 관(關)한 연구(硏究)
동국한의학연구소 논문집
1994 .01
-
Sodium Salicylate Inhibits Expression of COX-2 Through Suppression of ERK and Subsequent $NF-{\kappa}B$ Activation in Rat Ventricular Cardiomyocytes
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2003 .01
-
율피추출물의 사람 비만세포주 사이토카인 발현 억제 효과
대한본초학회지(본초분과학회지)
2013 .01
-
Biological Activity and Single Oral Dose Toxicity of Dansam-samultang
Laboratory Animal Research
2010 .12
-
목단피의 NF-κB와 MAPKs 억제를 통한 Pro-inflammatory Cytokines 활성에 미치는 효과
한방안이비인후피부과학회지
2009 .01
-
Vitamin C Blocks TNF-${\alpha}$-induced NF-kB Activation and ICAM-1 Expression in Human Neuroblastoma Cells
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
-
Regulatory Effect of Inflammatory Reaction by Asiasari Radix
동의생리병리학회지
2005 .01
-
Inhibition of TNF-a and IL-6 production by aucubin through blockade of NF-kB activation in RBL-2H3 mast cells
대한약학회 학술대회
2001 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0