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논문 기본 정보

자료유형
학술저널
저자정보
Huang, Hian L (Department of Nuclear Medicine and Molecular Imaging, Singapore General Hospital) Fong, Warren (Duke-NUS Medical School) Peh, Wee M (Department of Nuclear Medicine and Molecular Imaging, Singapore General Hospital) Niraj, Kasat A (Department of Nuclear Medicine and Molecular Imaging, Singapore General Hospital) Lam, Winnie W (Department of Nuclear Medicine and Molecular Imaging, Singapore General Hospital)
저널정보
대한핵의학회 Nuclear medicine and molecular imaging : NMMI Nuclear medicine and molecular imaging : NMMI 제52권 제1호
발행연도
2018.1
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53 - 61 (9page)

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Purpose Our case series aims to study the growing use of FDG PET/CT in diagnostic evaluation and follow up of IgG4-RD with emphasis on patients presenting with coronary artery involvement. Methods We conducted a search on the nuclear medicine and rheumatology service databases and identified patients with histologically proven IgG4-RD with FDG PET/CT performed at the Singapore General Hospital. The radiological, clinical, and laboratory findings of these patients were analyzed retrospectively. Results The series included ten male and two female patients. The commonest organ involved (five patients) was the pancreas. In three patients, coronary artery involvement manifested as soft tissue masses surrounding the arterial lumens. In these patients, histological diagnosis was established from alternative biopsy sites with abnormal metabolic activity on FDG PET/CT. Correlation between laboratory and metabolic imaging findings was not statistically significant in our series. Four patients had follow-up FDG PET/CT; three showed interval reduction in metabolic activity to baseline. One showed persistent abnormal metabolic activity before a rise in IgG4 levels. The metabolic imaging response was used to guide steroid dose. Conclusions FDG PET/CT is a useful tool in evaluation and follow-up of IgG4-RD, particularly in identifying alternative biopsy sites in patients who present with coronary artery involvement. Hypermetabolic coronary artery masses on FDG PET/CT should raise clinical suspicion of IgG4-RD. As the coronary artery masses may not show decrease in size after treatment, FDG PET/CT is also useful for metabolic response assessment.
#IgG4 #Fluorodeoxyglucose #Pet/Ct #Coronary artery

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참고문헌 (16)

참고문헌 신청
Lee TY / 2009 / Utility of 18F-FDG PET/CT for differentiation of autoimmune pancreatitis with atypical pancreatic imaging findings from pancreatic cancer / Am J Roentgenol 193:343~348 Crossref Nakatani K / 2012 / Utility of FDG PET/CT in IgG4-related systemic disease / Clin Radiol 67:297~305 Crossref Zhao Z / 2016 / Utility of FDG PET/CT in the diagnosis of IgG4-related diseases / Clin Exp Rheum 1:119~125 google schola Hourai R / 2016 / A case of IgG4-related lymphadenopathy, pericarditis, coronary artery periarteritis and luminal stenosis / Heart Vessel 31:1709~1713 Crossref Keraliya AR / 2016 / IgG4-Related disease with coronary arteritis / Circ Cardiovasc Imaging 9:e004583 Crossref

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