지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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To develop fundamental data of herbal materials with heat treatment, we studied analytical and extraction methods of benzopyrene in black ginseng and validated by HPLC analysis. Benzopyrene was successfully separated in mobile phase of acetonitrile:water (80 : 20) and detection of excitation 294 nm, emission 404 nm. The calibration curve of benzopyrene was linear over the concentration range of 1.17~37.50 ng/ml with correlation coefficient of above 0.999. The limit of detection (LOD) and quantitation (LOQ) of benzopyrene was 0.25 and 0.75 ng/ml, respectively. Hexane extraction method was used as a new extraction method for benzopyren and the efficient of extraction was over 95%. In conclusion, analytical method and extraction method were suitable for the determination of benzopyrene in the black ginseng and could be applied to fundamental study and guideline of herbal materials with heat treatment.
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참고문헌 (19)
참고문헌 신청
Columbia analytical services / 1999 / U.S. EPA METHOD 610- Polynuclear Aromatic Hydrocarbons : Methods for organic chemical analysis of municipal and industrial waste water
식품의약품안전평가원 / 2009 / 생약의 벤조피렌 시험법 해설서 :3
Shubik, P. / 1957 / Survey of compounds which have been tested for carcinogenic activity
Agency for Toxic Substances and Disease Registry (ATSDR) / 1995 / Toxicological profile for polycyclic aromatic hydrocarbons (PAHs) :1
Ahlbom, A. / 2004 / IARC Monographs on the evaluation of carcinogenic risks to humans
식품의약품안전평가원 / 2009 / 생약의 벤조피렌 시험법 해설서 :3
Shubik, P. / 1957 / Survey of compounds which have been tested for carcinogenic activity
Agency for Toxic Substances and Disease Registry (ATSDR) / 1995 / Toxicological profile for polycyclic aromatic hydrocarbons (PAHs) :1
Ahlbom, A. / 2004 / IARC Monographs on the evaluation of carcinogenic risks to humans
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