지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Background: World Health Organization considers opioid analgesic use as an important measure in the treatment of pain relief. However, there are limited data about the pattern of opioid analgesic use in tertiary care hospitals in Korea. The aim of this study was to describe the trends in the prescribed amount of the opioid for 13 years from 2000 to 2012 in a single tertiary care hospital. Methods: The data from the prescribed amount of opioid use in patients aged over 18 years were retrieved from medical charts and longitudinal pharmacy records of Seoul National University Hospital. Yearly prescribed amount of opioids were calculated using defined daily dose adjusted by hospital stay (DDD/1000${\bullet}$HS). Results: Over the 13 years of the study period, overall use of opioid has increased by 64.1%. Although, the opioid use by hospitalized patients comprised 98%~99% of total amount of opioid use, the proportions of opioid use by outpatient and by cancer patient increased from 1.1% to 2.2% and from 60.5% to 69.3%, respectively. The use of non-injectable opioids has increased by 47% and that of injectables has increased by 70%. While the amount of codeine and morphine use has decreased, the use of both transdermal and injection formulation of fentanyl has increased dramatically. Also, the use of oxycodone has increased, especially in outpatient setting. Conclusion: This longitudinal study showed that opioid analgesic use in tertiary hospital, especially in outpatient is continuously increasing. Improvement in pain management in tertiary care hospital can be cautiously inferred based on this results.
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참고문헌 (20)
참고문헌 신청
Cicero, T. J. / 2005 / Trends in abuse of Oxycontin and other opioid analgesics in the United States:2002-2004 / J. Pain 6:662
Cicero, T. J. / 2007 / Trends in the use and abuse of branded and generic extended release oxycodone and fentanyl products in the United States / Drug. Alcohol. Depend 91:115
Garcia del Pozo, J. / 2008 / Trends in the consumption of opioid analgesics in Spain. Higher increases as fentanyl replaces morphine / Eur. J. Clin. Pharmacol 64:411
Spiller, H. / 2009 / Epidemiological trends in abuse and misuse of prescription opioids / J. Addict. Dis 28:130
백진희 / 2013 / 의료용 마약류의 국내외 관리지침 비교분석을 통한 마약류의약품의 합리적 관리방안 연구 / 병원약사회지 30(2):141~156
Cicero, T. J. / 2007 / Trends in the use and abuse of branded and generic extended release oxycodone and fentanyl products in the United States / Drug. Alcohol. Depend 91:115
Garcia del Pozo, J. / 2008 / Trends in the consumption of opioid analgesics in Spain. Higher increases as fentanyl replaces morphine / Eur. J. Clin. Pharmacol 64:411
Spiller, H. / 2009 / Epidemiological trends in abuse and misuse of prescription opioids / J. Addict. Dis 28:130
백진희 / 2013 / 의료용 마약류의 국내외 관리지침 비교분석을 통한 마약류의약품의 합리적 관리방안 연구 / 병원약사회지 30(2):141~156
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