지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 제31권 제4호
- 발행연도
- 2008.1
- 수록면
- 523 - 529 (7page)
이용수
초록· 키워드
오류제보하기
A chiral mobile phase HPLC method is described for chiral separation and determination of chlorpheniramine (CP) enantiomers in various commercial preparations. Chromatographic separation was achieved on a conventional ODS column with a mixture of aqueous sodium phosphate (5 mM) containing 0.5 mM $carboxymethyl-{\beta}-cyclodextrin$, methanol and, triethylamine (73:25:2, v/v/v, pH 4.3) as the mobile phase. The flow rate of isocratic elution was 0,24 mL/min and peaks were detected at 224 nm. The method was applied to nine commercial CP preparations in six dosage forms and CP enantiomers were well separated without any disturbance of other ingredients or impurities present. The results showed that only one preparation was d-CP and the others were dl-CP preparations. The contents of all the preparations were found to be in the range of 97%-104% of labeled contents. This method was economical and convenient, affording sufficient accuracy, precision and reproducibility, as well as sensitivity and selectivity.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
모세관 전기영동법을 이용한 베타차단제-시클로덱스트린 포접화합물의 안정도상수 결정
약학회지
2003 .01
-
Enantiomer Separation of Chiral Drugs on HPLC Chiral Stationary Phases
대한약학회 학술대회
2002 .01
-
Chiral Separation of ${\beta}_2$-Agonists by Capillary Electrophoresis Using Hydroxypropyl-${\alpha}$-Cyclodextrin as a Chiral Selector
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2001 .01
-
HPLC Resolution of Enantiomers Using Polysaccharide Derivatives as Chiral Stationay Phases
대한약학회 학술대회
2002 .01
-
Chiral seperation of $\beta$2-agonists by Capillary electrophoresis using $\beta$-cyclodextrins as chiral selectors in a polyethylene glycol gel.
대한약학회 학술대회
2000 .01
-
Determination of Enantiomeric Impurity of Etodolac by Capillary Electrophoresis using (2-Hydroxypropyl)-$\beta$-cyclodextrin
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2008 .01
-
아스피린과민성 천식 환자에게 발생한 클로르페니라민 알레르기
천식 및 알레르기
2010 .01
-
Enantioselective stabilization of inclusion complexes of metoprolol in carboxymethylated beta-cyclodextrin
대한약학회 학술대회
2001 .01
-
Determination of Stability Constants of the Inclusion Complexes of ${\beta}$-Blockers in Heptakis (2,3-Dimethyl-6-Sulfato)- ${\beta}$-Cyclodextrin
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
-
Determination of Terbutaline Enantiomers in Human Urine by Capillary Electrophoresis Using $Hydroxypropyl-{\beta}-cyclodextrin$ as a Chiral Selector
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2003 .01
-
Development and Implementation of a Critical Pathway for Pediatric Inguinal Hernias
Annals of Surgical Treatment and Research
2008 .11
-
Glyceraldehyde-Derived Advanced Glycation End Products Accumulate Faster Than Nε-(Carboxymethyl) Lysine
Annals of Dermatology
2017 .01
-
Effects of Fexofenadine and Chlorpheniramine on the polysomnography
대한임상약리학회 학술대회
2006 .01
-
Does a Gradient-Adjusted Cardiac Power Index Improve Prediction of Post-Transcatheter Aortic Valve Replacement Survival Over Cardiac Power Index?
Yonsei Medical Journal
2020 .01
-
Chiral purity test of (R)-(-)-salbutamol by capillary electrophoresis using sulfated-{\beta}-cyclodextrin$ as a chiral selector
대한약학회 학술대회
2002 .01
-
Chiral Purity Test of Bevantolol by Capillaryelectrophoresis and High Performance Liquid Chromatography
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2006 .01
-
Resolution of Salbutamol Enantiomers in Human Urine by Reversed-Phase High Performance Liquid Chromatography after Derivatization with 2,3,4,6-Tetra-O-acetyl-${\beta}$-D-glucopyranosyl Isothiocyanate
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1998 .01
-
The interaction of zipeprol with $\beta$-cyclodextrin
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1987 .01
-
Enantiomeric Profiling Analysis of NSAIDs by Capillary Electrophoresis Using TM $\beta$-Cyclodextrin as the Chiral Selector
대한약학회 학술대회
2002 .01
-
Chiral Separation of Aromatic Acids by Capillary Electrophoresis Using HP $\beta$-Cyclodextrin as the Chiral Selector
대한약학회 학술대회
2002 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0