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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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초록· 키워드
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The aim of this study was to acquire level on the occurrence of five fluoroquinolones(FQs) residue among cultured eels in Jeonbuk province. Samples were collected from the four local area(Kunsan, Gochang, Wanju and Osu) and surveyed on the distribution of FQs residual level in edible muscle using HPLC method. A total of 90 samples of eel was monitored for detection of the FQs residue. Among them, 30 eels(33.3%) were detected the FQs single or paired, respectively. The detection ratios were showed Osu(40%, 8/20), Gochang(33%, 13/44), Wanju(30%, 6/20) and Kunsan(30%, 3/10) in order, respectively. The ratio was equivalent to over 30% of overall in sampled area. The most frequently detected FQs were perfloxacin(PF) followed by enrofloxacin(EF), ciprofloxacin(CF), ofloxacin(OF) and norfloxacin(NF). Eight different combinations of FQ residual patterns were observed as single(5 type, 21%) or as paired(3type, 12,5%) respectively and frequently encountered patterns were PF(37%) and PF-EF(23%). The residual level of FQs was evaluated in the range of 1-75 ug/kg and the most prevalent levels of FQs was found in 1-25 ug/kg(35 fish, 85%) followed by 26-50 ug/kg(5 fishes, 11%) and 51-75 ug/kg(1 fishes, 3.3%). These results could be possible that the cultured eels were mostly exposed with PF, EF and CF, and might be treated with a variety of fluoroquinolones for prevention of bacterial disease.
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참고문헌 (37)
참고문헌 신청
Austin, B.J. / 1983 / Control of furunculosis by oxonolic acid / Aquaculture 31:101~108
Clarke, A.M. / 1985 / In-vitro activity of pefloxacin compared to enoxacin, norfloxacin, gentamicin and new β-lactams. / J. Antimicro. Chemoth 15:39~46
EMEA(European Medicines Agency) / 2002 / The European agency for the evaluation of medicinal products veterinary medicines and inspections, committee for veterinary medical products, Enrofloxacin, Summary report
Barbosa, J. / 1998 / Retention behaviour of quinolone derivates in high-performance liquid chromatography effect of pH and evaluation of ionization constant / J. Chromatography. A 823:411~422
Barnes, A.C. / 1992 / Federation of europa microbiology society :3~5
Clarke, A.M. / 1985 / In-vitro activity of pefloxacin compared to enoxacin, norfloxacin, gentamicin and new β-lactams. / J. Antimicro. Chemoth 15:39~46
EMEA(European Medicines Agency) / 2002 / The European agency for the evaluation of medicinal products veterinary medicines and inspections, committee for veterinary medical products, Enrofloxacin, Summary report
Barbosa, J. / 1998 / Retention behaviour of quinolone derivates in high-performance liquid chromatography effect of pH and evaluation of ionization constant / J. Chromatography. A 823:411~422
Barnes, A.C. / 1992 / Federation of europa microbiology society :3~5
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