캠프 캐럴 인근 주민의 혈중 및 요중 휘발성 유기화합물 평가

임현술; 양원호; 김근배; 조용성; 민영선; 이관; 이덕희; 주영수; 김순신; 허정; 정다영

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자료유형: 학술저널

저자정보: 임현술 (동국의대예방의학교실) 양원호 (대구가톨릭대 산업보건학과) 김근배 (국립환경과학원환경보건연구과) 조용성 (국립환경과학원환경보건연구과) 민영선 (동국의대예방의학교실) 이관 (동국의대예방의학교실) 이덕희 (경북의대예방의학교실) 주영수 (한림의대성심병원직업환경의학과) 김순신 (대구가톨릭대 산업보건학과) 허정 (대구가톨릭대 산업보건학과) 정다영 (대구가톨릭대 산업보건학과)

저널정보: 한국산업보건학회 (구 한국산업위생학회) 한국산업보건학회지 한국산업보건학회지 제26권 제1호

발행연도: 2016.1

수록면: 11 - 19 (9page)

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Objectives: Exposure to volatile organic compounds such as trichloroethylene(TCE) and perchloroethylene(PCE), along with Agent Orange, that were issued around Camp Carroll US Army Base situated in Waegwan, Chilgok-gun, Gyeongsangbuk-do Province, Korea. The main objective of this study was to assess the exposure to TCE and PCE of residents of the area surrounding Camp Carroll. Methods: The TCE, PCE and trichloroethanol(TCEOH) concentrations in blood and trichlroroacetic acid(TCA) and TCEOH concentrations in urine were measured and analyzed in a total of 1,033 residents around Camp Carroll. TCA and TCEOH are metabolites of TCE and PCE, respectively. The information on demographic characteristics and exposure variables in relation to underground water were obtained through a questionnaire completed by the subjects. Results: TCE, PCE and TCEOH concentrations were not detected in blood. Detection rates of TCA and TECOH concentrations in urine were 98.5% and 36.6%, respectively. Creatinine-corrected average TCA and TCEOH concentrations were $12.23{\pm}23.81{\mu}g/g$ and $0.66{\pm}4.31{\mu}g/g$, respectively. A significant difference was not shown between the drinking group and no drinking group for underground water, which was assumed as a potential route of exposure to TCE and PCE through the consumption of ground water. However, females drinking ground water showed a significantly higher mean level of TCA in urine than did males. There was no significant difference according to drinking ground water as a potential source of exposure to TCE and PCE in residents around Camp Carroll. Conclusions: Considering the statistical analysis of factors affecting exposure to TCE and PCE in ground water along with previous reports, TCA in urine as exposure to TCE and PCE might not be appropriate because it is found in chlorinated drinking water. Therefore, TCA concentration in urine may be the result of drinking of chlorinated water.

#biomonitoring #exposure #groundwater #perchloroethylene #trichloroethylene

참고문헌 (26)

참고문헌 신청

Bader EL / 2004 / Urinary excretion half life of trichloroacetic acide as a biomarker of exposure to chlorinated drinking water disinfection by-products / Occup Environ Med 61:715~716

Calafat AM / 2003 / Urinary levels of trichloroacetic acid, a disinfection by-product in chlorinated drinking water in a human reference population / Environmental Health Perspectives 111:151~154

최병선 / 2002 / Trichloroethylene의 대사 및 간독성에 diethyldithiocarbamate가 미치는 영향 / Annals of Occupational and Environmental Medicine 14(3):257~269

Clausen J / 2004 / A case study of contaminants on military ranges: Camp Edwards, Massachusetts, USA / Environmental Pollution 129:13~21

Dehen B / 2000 / Tetrachloroethylene and trichloroethylene fatality: case report and simple headspace SPMEcapillary gas chromatographic determination in tissues / Journal of Analytical Toxicology 24:22~26

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