지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Pavlovian fear conditioning has been extensively studied for the understanding of neurobiological basis of memory and emotion. Pavlovian fear conditioning is an associative memory which forms when conditioned stimulus (CS) is paired with unconditioned stimulus (US) once or repeatedly. This behavioral model is also important for the understanding of anxiety disorders such as posttraumatic stress disorder. Here we describe the neural circuitry involved in fear conditioning and the molecular mechanisms underlying fear memory formation. During consolidation some memories fade out but other memories become stable and concrete. Emotion plays an important role in determining which memories will survive. Memory becomes unstable and editable again immediately after retrieval. It opens the possibility for us of modulating the established fear memory. It provides us with very efficient tools to improve the efficacy of cognitive-behavior therapy and other exposure-based therapy treating anxiety disorders.
목차
등록된 정보가 없습니다.
참고문헌 (94)
참고문헌 신청
Horgan J / 1999 / The undiscovered mind. 1st ed / Free Press :45
Phelps EA / 2005 / Contributions of the amygdala to emotion processing: from animal models to human behavior / Neuron 48:175~187
Raybuck JD / 2011 / Double dissociation of amygdala and hippocampal contributions to trace and delay fear conditioning / PLoS One 6:15982
LaBar KS / 1995 / Impaired fear conditioning following unilateral temporal lobectomy in humans / J Neurosci 15:6846~6855
Bechara A / 1995 / Double dissociation of conditioning and declarative knowledge relative to the amygdala and hippocampus in humans / Science 269:1115~1118
Phelps EA / 2005 / Contributions of the amygdala to emotion processing: from animal models to human behavior / Neuron 48:175~187
Raybuck JD / 2011 / Double dissociation of amygdala and hippocampal contributions to trace and delay fear conditioning / PLoS One 6:15982
LaBar KS / 1995 / Impaired fear conditioning following unilateral temporal lobectomy in humans / J Neurosci 15:6846~6855
Bechara A / 1995 / Double dissociation of conditioning and declarative knowledge relative to the amygdala and hippocampus in humans / Science 269:1115~1118
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