지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 35 - 41 (7page)
이용수
초록· 키워드
오류제보하기
Objectives : Hyeonggaeyeongyotang Gagambang (HYT) is a herbal medicine prescribed for the treatment of inflammatory diseases, but it is necessary to study the exact therapeutic efficacy. This study aims to investigate the antibacterial and anti-inflmmatory activities of HYT. Methods : Antibacterial activity of HYT was confirmed by staining Escherichia coli, a gram negative strain, and Staphylococcus aureus, a gram positive strain, on solid Lysogeny Broth (LB) medium containing HYT. Antioxidant activity of HYT was confirmed by 2,2'-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS) assay. The phosphorylation of nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha ($I{\kappa}B{\alpha}$) after lipopolysaccharide (LPS) treatment with HYT-treated RAW 264.7 mouse macrophages cells was confirmed by immunoblot analysis and the level of interleukin 1 beta (IL-$1{\beta}$) mRNA expression level was confirmed by quantitative real-time PCR. Results : HYT showed a concentration-dependent antibacterial activity against Escherichia coli and Staphylococcus aureus and also showed excellent antioxidant activity. HYT treatment attenuated the phosphorylation of $I{\kappa}B{\alpha}$induced by LPS treatment in RAW 264.7 mouse macrophages cells. The phosphorylation of $I{\kappa}B{\alpha}$is crucial for the regulation of the expression of various pro-inflammatory cytokines. In addition, IL-$1{\beta}$ mRNA expression level of RAW 264.7 mouse macrophages cells stimulated by LPS treatment was also inhibited by HYT treatment. Conclusions : Through experimental demonstration of the antioxidative, antimicrobial and anti-inflammatory effects of HYT, we demonstrated that HYT is a herbal medicine effective for the treatment of inflammatory diseases caused by various bacterial infections.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
형개연교탕(荊芥連翹湯) 가감방(가감방)의 발포정 제형 변화에 따른 약리학적 안정성 연구
대한본초학회지(본초분과학회지)
2018 .01
-
향사양위탕 혈맥약침이 항암요법으로 인한 구토반응 및 위운동 장애에 미치는 영향
혜화의학회지
2017 .01
-
Anti-inflammatory Effects of Complex Extract including Eucommia ulmoides in LPS-induced RAW 264.7 Cells
대한침구의학회지
2019 .01
-
Extract mulberry leaves fermented with Cordyceps militaris exerts anti inflammatory effects in LPS stimulated RAW264.7 macrophage cells by regulating COX-2/iNOS, inflammatory cytokine expression, MAP kinase pathways, the cell cycle and anti oxidant activity
한국실험동물학회 학술발표대회 논문집
2018 .07
-
Anti-inflammatory Effects of Ethanol Extract of Korean Medicinal Plants at Hwaak Mountain in LPS-induced RAW 264.7 Macrophages
대한본초학회지(본초분과학회지)
2017 .01
-
BO2, an extract of mixed natural plants inhibits inflammatory responses in LPS-stimulated Raw 264.7 macrophages
한국실험동물학회 학술발표대회 논문집
2016 .08
-
선학초(仙鶴草)추출물의 대식세포에서의 LPS-유도 염증반응에 대한 효능 연구
대한본초학회지(본초분과학회지)
2016 .01
-
Anti-inflammatory Activity of the Methanol Extract from the Stem of Coriandrum Sativum in RAW 264.7 Cells
대한본초학회지(본초분과학회지)
2018 .01
-
MOK, a Pharmacopuncture Medicine, Reduces Inflammatory Response through Inhibiting the Proinflammatory Cytokine Production in LPS-stimulated Mouse Peritoneal Macrophages
대한침구의학회지
2017 .01
-
RAW 264.7 대식세포에서 청뇌명신환(淸腦明神丸)에 의한 염증성 및 산화적 스트레스 반응 억제 효능
대한한의학방제학회지
2018 .01
-
LPS로 유발한 RAW264.7 세포 염증반응에 대한 가감통순산(加減通順散)의 억제 효과
한방재활의학과학회지
2018 .01
-
肉蓯蓉 열수추출물이 RAW 264.7 대식세포에 미치는 항염증 효과
한방안이비인후피부과학회지
2022 .02
-
Antioxidant and Anti-inflammatory Properties of Raw and Processed Fruits and Vegetables
대한의생명과학회지
2018 .09
-
RAW 264.7 세포에서 지모(知母) 80% 에탄올 추출물의 항염증 효과
대한본초학회지(본초분과학회지)
2017 .01
-
자초(紫草) 열수 추출물의 RAW 264.7 세포에서 IL-1β, TNF-α, iNOS 유전자 발현에 미치는 영향 연구
동의생리병리학회지
2017 .01
-
Viridicatol from Marine-derived Fungal Strain Penicillium sp. SF-5295 Exerts Anti-inflammatory Effects through Inhibiting NF-κB Signaling Pathway on Lipopolysaccharide-induced RAW264.7 and BV2 Cells
Natural Product Sciences
2015 .12
-
Anti-inflammatory and immune enhancing activities of PB203 in mouse macrophage RAW264.7 cells
Journal of Biomedical and Translational Research
2023 .06
-
Anti-inflammatory effect of the extract of black ginseng in LPS-stimulated Raw 264.7 macrophages
한국실험동물학회 학술발표대회 논문집
2016 .08
-
Anti-inflammatory Effects of Ethanol Extract of Various Korean Compositae Herbs in LPS-induced RAW 264.7 Macrophages
대한본초학회지(본초분과학회지)
2017 .01
-
Anti-Inflammatory Effects of Fermented Products with Avena sativa on RAW264.7 and HT-29 Cells via Inhibition of Inflammatory Mediators
Natural Product Sciences
2020 .09
이 논문의 저자 정보
최근 본 자료
댓글(0)
0