메뉴 건너뛰기
.. 내서재 .. 알림
소속 기관/학교 인증
인증하면 논문, 학술자료 등을  무료로 열람할 수 있어요.
한국대학교, 누리자동차, 시립도서관 등 나의 기관을 확인해보세요
(국내 대학 90% 이상 구독 중)
로그인 회원가입 고객센터 ENG
주제분류

추천
검색

논문 기본 정보

자료유형
학술저널
저자정보
Choi, Jae-Kyoung (Department of Animal Science and Technology, Chung-Ang University) Lim, Yea-Seul (Department of Animal Science and Technology, Chung-Ang University) Kim, Hee-Jin (Department of Animal Science and Technology, Chung-Ang University) Hong, Yeong-Ho (Department of Animal Science and Technology, Chung-Ang University) Ryu, Buom-Yong (Department of Animal Science and Technology, Chung-Ang University) Kim, Geun-Bae (Department of Animal Science and Technology, Chung-Ang University)
저널정보
한국축산식품학회 한국축산식품학회지 한국축산식품학회지 제32권 제5호
발행연도
2012.1
수록면
635 - 643 (9page)

이용수

표지
📌
연구주제
📖
연구배경
🔬
연구방법
🏆
연구결과
AI에게 요청하기
추천
검색

초록· 키워드

오류제보하기
As an appraisal for the application of a new starter culture, more than 200 lactic acid bacteria strains were isolated from raw milk and healthy human feces. The strains showing excellent growth and acid production ability in 10% skim milk media were selected and identified as Lactobacillus casei based on the results of their API carbohydrate fermentation patterns, as well as 16S rDNA sequence analysis. To assess the effect of L. casei strains on irritable bowel disease (IBD), the inhibitory effect of the selected strains against the nitric oxide (NO) production of lipopolysaccharide (LPS)-stimulated RAW 264.7 cells was measured. Among the tested L. casei strains, L. casei MCL was observed to have the greatest NO inhibitory activity. Additionally, L. casei MCL was found to inhibit mRNA expression of pro-inflammatory cytokines (interleukin-$1{\beta}$, IL-6, TNF-${\alpha}$), as well as cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) involved in pathophysiologic processes such as inflammation. The mRNA expression of anti-inflammatory cytokines, including IL-10 and transforming growth factor-$1{\beta}$ (TGF-${\beta}$) of L. casei MCL, was confirmed using quantitative real-time PCR. In conclusion, L. casei MCL showed decreases in the expression of pro-inflammatory cytokines and up-regulated expression of the anti-inflammatory cytokine.

목차

등록된 정보가 없습니다.

참고문헌 (36)

참고문헌 신청

이 논문의 저자 정보

최근 본 자료

전체보기

댓글(0)

0