지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Salmonella enterica serovar Typhimurium (ST) is one of the most common serovars isolated from humans and animals. It has been suggested that ST infections in Koreans are largely due to the consumption of contaminated pork and beef. To investigate the genotypes, phage types, and antimicrobial resistance patterns for ST isolates of different origins, a total of 70 ST strains, including 19 isolates from humans, 44 isolates from pigs, and 6 isolates from cattle, were analyzed using pulsedfield gel electrophoresis (PFGE), phage typing, and antimicrobial susceptibility tests. Forty-three distinct PFGE patterns were generated from 70 ST isolates, which were grouped into 14 PFGE groups (from A to N) at the level of 75% similarity. The most prevalent group was the A (A1-A17 subtypes) group, encompassing 54.5% (38/70) of ST isolates. ST isolates from pigs and cattle mostly belong to groups A and L, whereas ST isolates from humans mostly belong to groups F and C. Antimicrobial susceptibility tests using 11 antimicrobial agents showed that resistance to tetracycline (TE) (81.4%) was highly prevalent, followed by streptomycin (S) (64.3%) and nalidixic acid (NA) (31.4%) resistance. A total of seventeen antimicrobial resistance patterns were observed. Only 8.6% of isolates, including a reference strain, were susceptible to all antimicrobial agents tested. The most prevalent resistance pattern was TE-S (37.1%), which was seen in 66.6% of bovine, 40.8% of swine and 21.1% of human isolates. Three ST isolates from humans (15.9%) showed resistance to 7-8 antimicrobials. The most predominant phage type (PT) was U302 (64.3%), followed by DT170 (10.0%). PFGE types did not coincide with antimicrobial resistance patterns and phage types; therefore, the combination of those types allowed for further differentiation between tested ST isolates.
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참고문헌 (26)
참고문헌 신청
Anderson, E. S. / 1977 / Bacteriophage typing designation of SalmonellaTyphimurium / J. Hyg 78:297~300
Antunes, P. / 2003 / Incidence of Salmonella from poultry products andtheir susceptibility to antimicrobial agents / Int. J. FoodMicrobiol 82:97~103
Baggesen, D. L. / 2000 / Characterization of Salmonella enterica serovar TyphimuriumDT 104 isolated from Denmark and comparison withisolates from Europe and the United States / J. Clin. Microbiol 38:1581~1586
Bender, J. B. / 2001 / Use of molecular subtyping in surveillance for Salmonellaenterica serotype Typhimurium / New Engl. J. Med 344:189~195
Bessa, M. C. / 2007 / Phenotypic andgenetic characterization of Salmonella enterica subsp. entericaserovar Typhimurium isolated from pigs in Rio Grandedo Sul, Brazil / Res. Vet. Sci 83:302~310
Antunes, P. / 2003 / Incidence of Salmonella from poultry products andtheir susceptibility to antimicrobial agents / Int. J. FoodMicrobiol 82:97~103
Baggesen, D. L. / 2000 / Characterization of Salmonella enterica serovar TyphimuriumDT 104 isolated from Denmark and comparison withisolates from Europe and the United States / J. Clin. Microbiol 38:1581~1586
Bender, J. B. / 2001 / Use of molecular subtyping in surveillance for Salmonellaenterica serotype Typhimurium / New Engl. J. Med 344:189~195
Bessa, M. C. / 2007 / Phenotypic andgenetic characterization of Salmonella enterica subsp. entericaserovar Typhimurium isolated from pigs in Rio Grandedo Sul, Brazil / Res. Vet. Sci 83:302~310
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