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논문 기본 정보

자료유형
학술저널
저자정보
Ko, Seok-Jin (Department of Neurosurgery, Korea University Medical Center, College of Medicine, Korea University) Park, Kyung-Jae (Department of Neurosurgery, Korea University Medical Center, College of Medicine, Korea University) Park, Dong-Hyuk (Department of Neurosurgery, Korea University Medical Center, College of Medicine, Korea University) Kang, Shin-Hyuk (Department of Neurosurgery, Korea University Medical Center, College of Medicine, Korea University) Park, Jung-Yul (Department of Neurosurgery, Korea University Medical Center, College of Medicine, Korea University) Chung, Yong-Gu (Department of Neurosurgery, Korea University Medical Center, College of Medicine, Korea University)
저널정보
대한신경외과학회 대한신경외과학회지 대한신경외과학회지 제56권 제1호
발행연도
2014.1
수록면
34 - 41 (8page)

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Objective : The purpose of this study was to describe the clinical characteristics, treatment outcomes, and prognostic factors in patients with brain abscesses treated in a single institute during a recent 10-year period. Methods : Fifty-one patients with brain abscesses who underwent navigation-assisted abscess aspiration with antibiotic treatment were included in this study. Variable parameters were collected from the patients' medical records and radiological data. A comparison was made between patients with favorable [Glasgow Outcome Scale (GOS) ${\geq}4$] and unfavorable (GOS <4) outcomes at discharge. Additionally, we investigated the factors influencing the duration of antibiotic administration. Results : The study included 41 male and 10 female patients with a mean age of 53 years. At admission, 42 patients (82%) showed either clear or mildly disturbed consciousness (GCS ${\geq}13$) and 24 patients (47%) had predisposing factors. The offending microorganisms were identified in 25 patients (49%), and Streptococcus species were the most commonly isolated bacteria (27%). The mean duration of antibiotic administration was 42 days. At discharge, 41 patients had a favorable outcome and 10 had an unfavorable outcome including 8 deaths. The decreased level of consciousness (GCS <13) on admission was likely associated with an unfavorable outcome (p=0.052), and initial hyperglycemia (${\geq}140mg/dL$) was an independent risk factor for prolonged antibiotic therapy (p=0.032). Conclusion : We found that the level of consciousness at admission was associated with treatment outcomes in patients with brain abscesses. Furthermore, initial hyperglycemia was closely related to the long-term use of antibiotic agents.
#Brain abscess #Glasgow Coma Scale #Glasgow Outcome Scale #Hyperglycemia

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참고문헌 (34)

참고문헌 신청
Allport LE / 2004 / Insular cortical ischemia is independently associated with acute stress hyperglycemia / Stroke 35:1886~1891 google schola Arseni C / 1988 / Cerebral abscesses secondary to otorhinolaryngological infections. A study of 386 cases / Zentralbl Neurochir 49:22~36 google schola Barsoum AH / 1981 / Nonoperative treatment of multiple brain abscesses / Surg Neurol 16:283~287 google schola Calfee DP / 2000 / Brain abscess / Semin Neurol 20:353~360 google schola Capes SE / 2001 / Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients : a systematic overview / Stroke 32:2426~2432 google schola

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