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논문 기본 정보

자료유형
학술저널
저자정보
Shin, Jung-Hoon (Department of Neurosurgery, Dongsan Medical Center, Keimyung University School of Medicine) Jung, Na-Young (Department of Neurosurgery, Dongsan Medical Center, Keimyung University School of Medicine) Kim, Sang-Pyo (Department of Pathology, Dongsan Medical Center, Keimyung University School of Medicine) Son, Eun-Ik (Department of Neurosurgery, Dongsan Medical Center, Keimyung University School of Medicine)
저널정보
대한신경외과학회 대한신경외과학회지 대한신경외과학회지 제56권 제3호
발행연도
2014.1
수록면
248 - 253 (6page)

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Objective : Cortical dysplasia (CD) is one of the common causes of epilepsy surgery. However, surgical outcome still remains poor, especially with frontal lobe epilepsy (FLE), despite the advancement of neuroimaging techniques and expansion of surgical indications. The aim of this study was to focus on surgical strategies in terms of extent of resection to improve surgical outcome in the cases of FLE with CD. Methods : A total of 11 patients of FLE were selected among 67 patients who were proven pathologically as CD, out of a total of 726 epilepsy surgery series since 1992. This study categorized surgical groups into three according to the extent of resection : 1) focal corticectomy, 2) regional corticectomy, and 3) partial functional lobectomy, based on the preoperative evaluation, in particular, ictal scalp EEG onset and/or intracranial recordings, and the lesions in high-resolution MRI. Surgical outcome was assessed following Engel's classification system. Results : Focal corticectomy was performed in 5 patients and regional corticectomy in another set of 5 patients. Only 1 patient underwent partial functional lobectomy. Types I and II CD were detected with the same frequency (45.45% each) and postoperative outcome was fully satisfactory (91%). Conclusion : The strategy of epilepsy surgery is to focus on the different characteristics of each individual, considering the extent of real resection, which is based on the focal ictal onset consistent with neuroimaging, especially in the practical point of view of neurosurgery.
#Epilepsy surgery #Frontal lobe epilepsy #Cortical dysplasia

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참고문헌 (36)

참고문헌 신청
Awad IA / 1991 / Intractable epilepsy and structural lesions of the brain : mapping, resection strategies, and seizure outcome / Epilepsia 32:179~186 google schola Barkovich AJ / 1996 / Neuroimaging of focal malformations of cortical development / J Clin Neurophysiol 13:481~494 google schola Bautista RE / 1999 / Prediction of surgical outcome by interictal epileptiform abnormalities during intracranial EEG monitoring in patients with extrahippocampal seizures / Epilepsia 40:880~890 google schola Becker AJ / 2006 / Molecular neuropathology of epilepsy-associated glioneuronal malformations / J Neuropathol Exp Neurol 65:99~108 google schola Blümcke I / 2011 / The clinicopathologic spectrum of focal cortical dysplasias : a consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission / Epilepsia 52:158~174 google schola

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