The Comparison of Clinical Variables in Two Classifications: GOLD 2017 Combined Assessment and Spirometric Stage of Chronic Obstructive Pulmonary Disease

Candemir, Ipek; Ergun, Pinar; Kaymaz, Dicle; Tasdemir, Filiz; Egesel, Nurcan

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저자정보: Candemir, Ipek (Ataturk Chest Diseases and Chest Surgery Education and Research Hospital, Pulmonary Rehabilitation and Home Care Center) Ergun, Pinar (Ataturk Chest Diseases and Chest Surgery Education and Research Hospital, Pulmonary Rehabilitation and Home Care Center) Kaymaz, Dicle (Ataturk Chest Diseases and Chest Surgery Education and Research Hospital, Pulmonary Rehabilitation and Home Care Center) Tasdemir, Filiz (Ataturk Chest Diseases and Chest Surgery Education and Research Hospital, Pulmonary Rehabilitation and Home Care Center) Egesel, Nurcan (Ataturk Chest Diseases and Chest Surgery Education and Research Hospital, Pulmonary Rehabilitation and Home Care Center)

저널정보: 대한결핵 및 호흡기학회 Tuberculosis and Respiratory Diseases 결핵 및 호흡기 질환 제81권 제4호

발행연도: 2018.1

수록면: 281 - 288 (8page)

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Background: There are limited number of studies that investigate clinical variables instead of chronic obstructive lung disease (COPD) management according to Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 classification. The aim of the study was to investigate whether there was a difference between GOLD 2017 classification and spirometric stage in clinical variables in patients with COPD. The data of 427 male patients with stable COPD were investigated retrospectively. Methods: Patients were allocated into combined assessment of GOLD 2017 and spirometric stage. Age, amount of smoking, pulmonary function, modified Medical Research Council (mMRC), incremental shuttle walk test (ISWT), Hospital Anxiety-Depression Scale (HADS), St. George's Respiratory Questionnaire (SGRQ), body mass index (BMI), and fat free mass index (FFMI) were recorded. Results: Seventy-three (17%) patients were in group A, 103 (24%) constituted group B, 38 (9%) were included in group C, and 213 (50%) comprised group D according to the combined assessment of GOLD 2017. Twenty-three patients (5%) were in stage 1, 95 (22%) were in stage 2, 149 (35%) were in stage 3, and 160 (38%) were in stage 4 according to spirometric stage. According to GOLD 2017, age, amount of smoking, mMRC, BMI, FFMI, SGRQ, HADS, forced vital capacity, forced expiratory volume in 1 second ($FEV_1$), and ISWT were significantly different between groups. Ages, amount of smoking, FFMI, BMI, HADS of group A were different from B and D. Smiliar values of $FEV_1$ were found in A-C and B-D. A and C had smiliar ISWT. According to spirometric stage, BMI, FFMI of stage 4 were statistically different. mMRC, ISWT, and SGRQ of stages 3 and 4 were different from other stages, amongst themselves. $FEV_1$ was correlated with mMRC, SGRQ, anxiety scores, BMI, FFMI, and ISWT. Conclusion: This study showed that the GOLD ABCD classification might not represent the severity of COPD sufficiently well in terms of lung function or exercise capacity. The combination of both spirometric stage and combined assessment of GOLD 2017 is important, especially for estimating clinical variables.

#Pulmonary Disease, Chronic Obstructive #Quality of Life #Dyspnea

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