지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 35 - 39 (5page)
이용수
초록· 키워드
오류제보하기
Purpose: This study compared the efficacy and tolerability of intravenous (i.v.) phenobarbital (PHB) and i.v. levetiracetam (LEV) in children with status epilepticus (SE) or acute repetitive seizure (ARS). Methods: The medical records of children (age range, 1 month to 15 years) treated with i.v. PHB or LEV for SE or ARS at our single tertiary center were retrospectively reviewed. Seizure termination was defined as seizure cessation within 30 minutes of infusion completion and no recurrence within 24 hours. Information on the demographic variables, electroencephalography and magnetic resonance imaging findings, previous antiepileptic medications, and adverse events after drug infusion was obtained. Results: The records of 88 patients with SE or ARS (median age, 18 months; 50 treated with PHB and 38 with LEV) were reviewed. The median initial dose of i.v. PHB was 20 mg/kg (range, 10-20 mg/kg) and that of i.v. LEV was 30 mg/kg (range, 20-30 mg/kg). Seizure termination occurred in 57.9% of patients treated with i.v. LEV (22 of 38) and 74.0% treated with i.v. PHB (37 of 50) (P=0.111). The factor associated with seizure termination was the type of event (SE vs. ARS) in each group. Adverse effects were reported in 13.2% of patients treated with i.v. LEV (5 of 38; n=4, aggressive behavior and n=1, vomiting), and 28.0% of patients treated with i.v. PHB (14 of 50). Conclusion: Intravenous LEV was efficacious and safe in children with ARS or SE. Further evaluation is needed to determine the most effective and best-tolerated loading dose of i.v. LEV.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Short-Term and Long-Term Effects of Levetiracetam Monotherapy on Homocysteine Metabolism in Children with Epilepsy: A Prospective Study
Journal of Clinical Neurology
2019 .01
-
The Influence of Levetiracetam in Cognitive Performance in Healthy Individuals: Neuropsychological, Behavioral and Electrophysiological Approach
Clinical Psychopharmacology and Neuroscience
2015 .01
-
Seizure Aggravation Following Adjunctive Levetiracetam Therapy in Children with Epilepsy: a Single Tertiary Center Experience
대한소아신경학회지
2017 .01
-
Implementation and Validation of an Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry Method for Quantifying Levetiracetam and Lamotrigine in Serum Specimens
Journal of Laboratory Medicine And Quality Assurance
2022 .12
-
Non-Convulsive Status Epilepticus following Liver Transplantation
Acute and Critical Care
2016 .01
-
인플루엔자 감염으로 유발된 경련의 임상적 특징
대한소아신경학회지
2015 .09
-
Status Epilepticus and Beyond: A Clinical Review of Status Epilepticus and an Update on Current Management Strategies in Super-refractory Status Epilepticus
Acute and Critical Care
2017 .01
-
Mental Change, Seizure
대한외과학회 학술대회 초록집
2019 .10
-
Low-dose Clozapine-induced Seizure: A Case Report
Clinical Psychopharmacology and Neuroscience
2017 .01
-
1p36 Deletion syndrome Presenting with Various Epileptic Semiologies
대한소아신경학회지
2015 .12
-
소아 뇌전증 환자에서 항경련제 치료 후 재발의 위험인자
대한소아신경학회지
2016 .09
-
Respiratory syncytial virus-associated seizures in Korean children, 2011-2016
Clinical and Experimental Pediatrics
2019 .01
-
소아 발작 질환에 대한 국내 임상논문 고찰
대한한방소아과학회지
2020 .01
-
Antiepileptic Drugs in Children : Current Concept
대한신경외과학회지
2019 .01
-
Epilepsy in children with a history of febrile seizures
Clinical and Experimental Pediatrics
2016 .01
-
Febrile Seizure Associated With COVID-19 in a Child: Case Report and Literature Review
Pediatric Infection and Vaccine
2024 .04
-
A Case of Generalized Seizure after Toxic Epidermal Necrolysis
Annals of Dermatology
2020 .01
-
Correlation of serum S100B levels with brain magnetic resonance imaging abnormalities in children with status epilepticus
Clinical and Experimental Pediatrics
2019 .01
-
Episodes of prolonged “trance-like state” in an infant with hypothalamic hamartoma
Annals of Pediatirc Endocrinology & Metabolism
2019 .01
-
Extracellular vesicles from Lactobacillus sakei prevent RANKL-induced osteoclast differentiation
한국실험동물학회 학술발표대회 논문집
2021 .07
이 논문의 저자 정보
최근 본 자료
댓글(0)
0