지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Objectives : This study was aimed to compare Gyejibokryeong-hwan (GBH) decoctions produced using different pressure levels for various extraction times to find the optimal extraction conditions through extraction yield, total soluble solids content (TSSC), hydrogen ion concentration (pH), and the contents of chemical compounds. Methods : Decoctions of GBH were prepared under the pressure levels of 0 or $1kgf/cm^2$ for 30-180 min using water as extraction solvent. The extraction yield, TSSC, and pH were measured, and the amounts of the chemical compounds were determined using high performance liquid chromatography-photodiode array detector. Results : The higher pressure and longer extraction time increased the values of TSSC and extraction yield, while decreased the pH value. The decoctions produced in 180 min by pressurized method and produced in 150 min by non-pressurized method showed maximum values of extraction yield and TSSC with minimum value of pH. The amounts of chemical compounds showed variations in pressurized and non-pressurized decoction during overall extraction times. The influences of pressure and extraction time on extraction yield, TSSC, pH, and the contents of chemical compounds were confirmed by regression analysis, which showed that all extraction values were significantly affected by at least one of two extraction factors, pressure and extraction time. Conclusions : This study suggests that the pressure and extraction time can significantly affect the extraction efficiency of components from GBH decoctions. However, optimal extraction conditions could not be chosen due to the variation of the amounts of chemical compounds.
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참고문헌 (20)
참고문헌 신청
Sakamoto S / 1992 / Pharmacotherapeutic effects of kuei-chih-fu-ling-wan (keishi-bukuryo-gan) on human uterine myomas / Am J Chin Med 20(3):313~317
Sang H / 2004 / Clinical and experimental research into treatment of hysteromyoma with promoting qi flow and blood circulation, softening and resolving hard lump / J Traditi Chin Med 24(4):274~279
Ushiroyama T / 2005 / Comparing the effects of estrogen and an herbal medicine on peripheral blood flow in post-menopausal women with hot flashes: hormone replacement therapy and gui-zhi-fu-ling-wan, a Kampo medicine / Am J Chin Med 33(2):259~267
Zhang S / 2006 / Ginsenoside extraction from Panax quinquefolium L. (American ginseng) root by using ultrahigh pressure / J Pharm Biomed Anal 41(1):57~63
Egizabal A / 1998 / Comparison of microwave-assisted extraction and Soxhlet extraction for phenols in soil samples using experimental designs / Analyst 123:1679~1684
Sang H / 2004 / Clinical and experimental research into treatment of hysteromyoma with promoting qi flow and blood circulation, softening and resolving hard lump / J Traditi Chin Med 24(4):274~279
Ushiroyama T / 2005 / Comparing the effects of estrogen and an herbal medicine on peripheral blood flow in post-menopausal women with hot flashes: hormone replacement therapy and gui-zhi-fu-ling-wan, a Kampo medicine / Am J Chin Med 33(2):259~267
Zhang S / 2006 / Ginsenoside extraction from Panax quinquefolium L. (American ginseng) root by using ultrahigh pressure / J Pharm Biomed Anal 41(1):57~63
Egizabal A / 1998 / Comparison of microwave-assisted extraction and Soxhlet extraction for phenols in soil samples using experimental designs / Analyst 123:1679~1684
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