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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 102 - 113 (12page)
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Metagenomics has become one of the indispensable tools in microbial ecology for the last few decades, and a new revolution in metagenomic studies is now about to begin, with the help of recent advances of sequencing techniques. The massive data production and substantial cost reduction in next-generation sequencing have led to the rapid growth of metagenomic research both quantitatively and qualitatively. It is evident that metagenomics will be a standard tool for studying the diversity and function of microbes in the near future, as fingerprinting methods did previously. As the speed of data accumulation is accelerating, bioinformatic tools and associated databases for handling those datasets have become more urgent and necessary. To facilitate the bioinformatics analysis of metagenomic data, we review some recent tools and databases that are used widely in this field and give insights into the current challenges and future of metagenomics from a bioinformatics perspective.
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참고문헌 (109)
참고문헌 신청
Handelsman J / 1998 / Molecular biological access to the chemistry of unknown soil microbes: a new frontier for natural products / Chem Biol 5:R245~R249
Béjà O / 2000 / Bacterial rhodopsin: evidence for a new type of phototrophy in the sea / Science 289:1902~1906
Fuhrman JA / 2008 / A latitudinal diversity gradient in planktonic marine bacteria / Proc Natl Acad Sci U S A 105:7774~7778
Fierer N / 2012 / Cross-biome metagenomic analyses of soil microbial communities and their functional attributes / Proc Natl Acad Sci U S A 109:21390~21395
Metzker ML / 2010 / Sequencing technologies: the next generation / Nat Rev Genet 11:31~46
Béjà O / 2000 / Bacterial rhodopsin: evidence for a new type of phototrophy in the sea / Science 289:1902~1906
Fuhrman JA / 2008 / A latitudinal diversity gradient in planktonic marine bacteria / Proc Natl Acad Sci U S A 105:7774~7778
Fierer N / 2012 / Cross-biome metagenomic analyses of soil microbial communities and their functional attributes / Proc Natl Acad Sci U S A 109:21390~21395
Metzker ML / 2010 / Sequencing technologies: the next generation / Nat Rev Genet 11:31~46
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