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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 162 - 176 (15page)
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초록· 키워드
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This study was performed to evaluate the antioxidant activity of yogurt fermented at low temperature and the anti-inflammatory effect it has on induced colitis with 2.5% dextran sodium sulfate (DSS) in Balb/c mice. Yogurt premix were fermented with a commercial starter culture containing Lactobacillus acidophilus, Bifidobacterium lactis, Streptococcus thermophilus, and Lactobacillus delbrueckii subsp. bulgaricus at different temperatures: $22^{\circ}C$ (low fermentation temperature) for 27 h and $37^{\circ}C$ (general fermentation temperature) for 12 h. To measure antioxidant activity of yogurt samples, DPPH, $ABTS^+$ and ferric reducing antioxidant potential (FRAP) assays were conducted. For animal experiments, inflammation was induced with 2.5% DSS in Balb/c mice. Yogurt fermented at low temperature showed higher antioxidant activity than that of the yogurt fermented at general temperature. In the inflammatory study, IL-6 (interleukin 6) was decreased and IL-4 and IL-10 increased significantly in DSS group with yogurt fermented at general temperature (DYG) and that with yogurt fermented at low temperature (DYL) compared to that in DSS-induced colitic mice (DC), especially DYL had higher concentration of cytokines IL-4, and IL-10 than DYG. MPO (myeloperoxidase) tended to decrease more in treatments with yogurt than DC. Additionally, yogurt fermented at low temperature had anti-inflammatory activity, although there was no significant difference with general temperature-fermented yogurt (p>0.05).
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참고문헌 (49)
참고문헌 신청
Adolfsson O / 2004 / Yogurt and gut function / Am J Clin Nutr 80:245~256
Baroja ML / 2007 / Anti-inflammatory effects of probiotic yogurt in inflammatory bowel disease patients / Clin Exp Immunol 149:470~479
Benzie IFF / 1996 / The ferric reducing ability of plasma(FRAP)as a measure of"antioxidant power" : The FRAP assay / Anal Biochem 239:70~76
Blois MS / 1958 / Antioxidant determinations by the use of a stable free radical / Nature 181:1199~1200
Campieri M / 2000 / Combination of antibiotic and probiotic treatment is efficacious in prophylaxis of post-operative recurrence of Crohn’s disease : A randomised controlled study vs mesalamine / Gastroenterology 118:4179
Baroja ML / 2007 / Anti-inflammatory effects of probiotic yogurt in inflammatory bowel disease patients / Clin Exp Immunol 149:470~479
Benzie IFF / 1996 / The ferric reducing ability of plasma(FRAP)as a measure of"antioxidant power" : The FRAP assay / Anal Biochem 239:70~76
Blois MS / 1958 / Antioxidant determinations by the use of a stable free radical / Nature 181:1199~1200
Campieri M / 2000 / Combination of antibiotic and probiotic treatment is efficacious in prophylaxis of post-operative recurrence of Crohn’s disease : A randomised controlled study vs mesalamine / Gastroenterology 118:4179
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