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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 458 - 466 (9page)
이용수
초록· 키워드
오류제보하기
Objective : To compare peri-operative any symptomatic stroke after carotid angioplasty and stenting (CAS), based on the application or absence of a cerebral protection device. Methods : A systematic literature review using PubMed, Embase, and the Cochrane Central was done across an online data base from January 1995 to October 2016. Procedures which were performed due to carotid dissection or aneurysm, procedures using covered stents or conducted in an emergency, were excluded. The primary endpoint was perioperative any symptomatic stroke within 30 days after the procedure. A fixed effect model was used in cases of heterogeneity less than 50%. Results : In the 25 articles included in this study, the number of stroke events was 326 (2.0%) in protected CAS and 142 (3.4%) in unprotected CAS. The use of cerebral protection device significantly decreased stroke after CAS (odds ratio [OR] 0.633, 95% confidence interval [CI] 0.479-0.837, p=0.001). In the publication bias analysis, Egger's regression test disclosed that the intercept was -0.317 (95% CI -1.015-0.382, p=0.358). Regarding symptomatic patients (four studies, 539 CAS procedures), the number of stroke was six (1.7%) in protected CAS and 11 (5.7%) in unprotected CAS. The protective effect against stroke events by cerebral protection device did not have a statistical significance (OR 0.455, 95% CI 0.151-1.366, p=0.160). Conclusion : The use of protection device significantly decreased stroke after CAS. However, its efficacy was not demonstrated in symptomatic patients. Routine use of protection device during CAS should be critically assessed before mandatory use.
목차
등록된 정보가 없습니다.
참고문헌 (45)
참고문헌 신청
Al-Mubarak N / 2001 / Effect of the distal-balloon protection system on microembolization during ca- rotid stenting / Circulation 104:1999~2002
Barbato JE / 2008 / A randomized trial of carotid artery stenting with and without cerebral protection / J Vasc Surg 47:760~765
Begg CB / 1994 / Operating characteristics of a rank correlation test for publication bias / Biometrics 50:1088~1101
Boltuch J / 2005 / Procedure-related complications and early neurological adverse events of unprotected and protected carotid stenting: temporal trends in a consecutive patient series / J Endovasc Ther 12:538~547
Bonati LH / 2012 / Percutaneous transluminal balloon angioplasty and stenting for carotid artery stenosis / Cochrane Database Syst Rev (9)
Barbato JE / 2008 / A randomized trial of carotid artery stenting with and without cerebral protection / J Vasc Surg 47:760~765
Begg CB / 1994 / Operating characteristics of a rank correlation test for publication bias / Biometrics 50:1088~1101
Boltuch J / 2005 / Procedure-related complications and early neurological adverse events of unprotected and protected carotid stenting: temporal trends in a consecutive patient series / J Endovasc Ther 12:538~547
Bonati LH / 2012 / Percutaneous transluminal balloon angioplasty and stenting for carotid artery stenosis / Cochrane Database Syst Rev (9)
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