지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 163 - 166 (4page)
이용수
초록· 키워드
오류제보하기
The prophylactic use of phenytoin during and after brain surgery and cranial irradiation is a common measure in brain tumor therapy. Phenytoin has been associated with variety of adverse skin reactions including urticaria, erythroderma, erythema multiforme (EM), Stevens-Johnson syndrome, and toxic epidermal necrolysis. EM associated with phenytoin and cranial radiation therapy (EMPACT) is a rare specific entity among patients with brain tumors receiving radiation therapy while on prophylactic anti-convulsive therapy. Herein we report a 41-year-old female patient with left temporal glial tumor who underwent surgery and then received whole brain radiation therapy and chemotherapy. After 24 days of continous prophylactic phenytoin therapy the patient developed minor skin reactions and 2 days later the patient returned with generalized erythamatous and itchy maculopapuler rash involving neck, chest, face, trunk, extremities. There was significant periorbital and perioral edema. Painful mucosal lesions consisting of oral and platal erosions also occurred and prevented oral intake significantly. Phenytoin was discontinued gradually. Systemic admistration of corticosteroids combined with topical usage of steroids for oral lesions resulted in complete resolution of eruptions in 3 weeks. All cutaneous lesions in patients with phenytoin usage with the radiotherapy must be evoluated with suspicion for EM.
목차
등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
Ahmed I. / 2004 / Erythema multiforme associated with phenytoin and cranial radiation therapy : a report of three patients and review of the literature / Int J Dermatol 43:67~73
Arif H. / 2007 / Comparison and predictors of rash associated with 15 antiepileptic drugs / Neurology 68:1701~1709
Baba M. / 2003 / The anticonvulsant hypersensitivity syndrome / J Eur Acad Dermatol Venereol 17:399~401
Barbosa LA. / 2008 / Erythema multiforme associated with prophylactic use of phenytoin during cranial radiation therapy / Am J Health Syst Pharm 65:1048~1050
Lin MS. / 2005 / Risk estimates for drugs suspected of being associated with Stevens-Johnson syndrome and toxic epidermal necrolysis : a case-control study / Intern Med J 35:188~190
Arif H. / 2007 / Comparison and predictors of rash associated with 15 antiepileptic drugs / Neurology 68:1701~1709
Baba M. / 2003 / The anticonvulsant hypersensitivity syndrome / J Eur Acad Dermatol Venereol 17:399~401
Barbosa LA. / 2008 / Erythema multiforme associated with prophylactic use of phenytoin during cranial radiation therapy / Am J Health Syst Pharm 65:1048~1050
Lin MS. / 2005 / Risk estimates for drugs suspected of being associated with Stevens-Johnson syndrome and toxic epidermal necrolysis : a case-control study / Intern Med J 35:188~190
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Treatment of Drug-Induced Erythema Multiforme: Case Report
Journal of Oral Medicine and Pain
2019 .12
-
The Molecular Subtype Dependent Effect of Concurrent Radiotherapy and Systemic Therapy on Breast Cancer: Analysis of a Human In Vivo Model of Metastatic Brain Lesions
Journal of Breast Disease
2016 .12
-
Brain Metastases from Solid Tumors: an Institutional Study from South India
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Cranial Nerve Disorders: Clinical Application of High-Resolution Magnetic Resonance Imaging Techniques
Investigative Magnetic Resonance Imaging
2021 .12
-
Efficacy of Mirror Therapy Containing Functional Tasks in Poststroke Patients
Annals of Rehabilitation Medicine
2016 .01
-
음성장애환자의 음성치료 후 만족도 연구
대한후두음성언어의학회지
2016 .01
-
Successful Treatment of Advanced Gastric Cancer with Brain Metastases through an Abscopal Effect by Radiation and Immune Checkpoint Inhibitor Therapy
Journal of Gastric Cancer
2021 .09
-
Cranial Index in a Modern Thai Population
대한체질인류학회 학술대회 연제 초록
2017 .06
-
MRI 영상 유도 수술 로봇을 위한 개선된 군집 분석 방법을 이용한 뇌종양 영역 검출 개발
의공학회지
2019 .01
-
Treatment of Stevens-Johnson syndrome
Oral Biology Research
2016 .01
-
Intensive Rehabilitation Therapy Following Brain Tumor Surgery: A Pilot Study of Effectiveness and Long-Term Satisfaction
Annals of Rehabilitation Medicine
2019 .01
-
Effect of Integrated Cognitive Intervention Therapy in Patients with Mild to Moderate Alzheimer's Disease
Dementia and Neurocognitive Disorders(대한치매학회지)
2020 .01
-
Radiation Therapy Outcome and Clinical Features of Duodenal-Type Follicular Lymphoma
Cancer Research and Treatment
2019 .01
-
표적항암치료의 부작용 관리
대한의사협회지
2023 .02
-
Sorafenib Induces Delayed-Onset Cutaneous Hypersensitivity: A Case Series
Allergy, Asthma & Immunology Research
2015 .01
-
Dysphagia after Multiple Lower Cranial Nerves Palsy Induced by Inflammatory Lesion: A Case Report
대한근전도 전기진단의학회지
2018 .01
-
Radiation Therapy against Pediatric Malignant Central Nervous System Tumors : Embryonal Tumors and Proton Beam Therapy
대한신경외과학회지
2018 .01
-
Sinonasal Teratocarcinosarcoma, a Rare Tumor Involving Both the Nasal Cavity and the Cranial Cavity
Brain Tumor Research and Treatment
2020 .01
-
Proton Therapy Review: Proton Therapy from a Medical
의학물리
2020 .01
-
Chemotherapy and targeted therapy
대한외과학회 학술대회 초록집
2016 .11
이 논문의 저자 정보
최근 본 자료
댓글(0)
0