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자료유형
학술저널
저자정보
Cho, Won-Ho (Department of Neurosurgery, Medical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine) Choi, Young-Jin (Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine) Choi, Byung-Kwan (Department of Neurosurgery, Medical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine) Cha, Seung-Heon (Department of Neurosurgery, Medical Research Institute, Pusan National University Hospital, Pusan National University School of Medicine)
저널정보
대한신경외과학회 대한신경외과학회지 대한신경외과학회지 제47권 제5호
발행연도
2010.1
수록면
385 - 388 (4page)

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Intracranial granulocytic sarcomas are rare tumors, which are composed of immature granulocytic cells. Although it has been well known that these tumors are associated with acute myeloblastic leukemia (AML), they have been almost always related to bone marrow relapse. However, isolated recurrence of granulocytic sarcoma following complete remission from prior AML is extremely rare, especially in the central nervous system. A 44-year-old male presented with isolated recurrence of granulocytic sarcoma mimicking a falx meningioma two years after complete remission by allogenic peripheral blood stem cell transfusion (PBSCT) in the acute myelomonoblastic leukemia (FAB, M4). Because of depressed mental state and mass effect, total surgical resection was performed. Pathological findings were compatible with the granulocytic sarcoma. There was no evidence of leukemic relapse in the peripheral blood. We suggest that this phenomenon can be explained by the hypothesis that a certain barrier effect such as blood brain barrier might lead to the proliferation of intracranial leukemic cells which metastasized before PBSCT.

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