지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
Objective : The incidence and prevalence of spinal metastases are increasing, and although the role of radiation therapy in the treatment of metastatic tumors of the spine has been well established, the same cannot be said about the role of stereotactic radiosurgery. Herein, the authors present a systematic review regarding the value of spinal stereotactic radiosurgery in the management of spinal metastasis. Methods : A systematic literature search for stereotactic radiosurgery of spinal metastases was undertaken. Grades of Recommendation, Assessment, Development, and Education (GRADE) working group criteria was used to evaluate the qualities of study datasets. Results : Thirty-one studies met the study inclusion criteria. Twenty-three studies were of low quality, and 8 were of very low quality according to the GRADE criteria. Stereotactic radiosurgery was reported to be highly effective in reducing pain, regardless of prior treatment. The overall local control rate was approximately 90%. Additional asymptomatic lesions may be treated by stereotactic radiosurgery to avoid further irradiation of neural elements and further bone-marrow suppression. Stereotactic radiosurgery may be preferred in previously irradiated patients when considering the radiation tolerance of the spinal cord. Furthermore, residual tumors after surgery can be safely treated by stereotactic radiosurgery, which decreases the likelihood of repeat surgery and accompanying surgical morbidities. Encompassing one vertebral body above and below the involved vertebrae is unnecessary. Complications associated with stereotactic radiosurgery are generally self-limited and mild. Conclusion : In the management of spinal metastasis, stereotactic radiosurgery appears to provide high rates of tumor control, regardless of histologic diagnosis, and can be used in previously irradiated patients. However, the quality of literature available on the subject is not sufficient.
목차
등록된 정보가 없습니다.
참고문헌 (43)
참고문헌 신청
Benzil DL / 2004 / Safety and efficacy of stereotactic radiosurgery for tumors of the spine / J Neurosurg 101(Suppl 3):413~418
Bernstein EF / 1993 / Biology of chronic radiation effect on tissues and wound healing / Clin Plast Surg 20:435~453
Chang EL / 2007 / Phase I/II study of stereotactic body radiotherapy for spinal metastasis and its pattern of failure / J Neurosurg Spine 7:151~160
Choi CY / 2010 / Stereotactic radiosurgery for treatment of spinal metastases recurring in close proximity to previously irradiated spinal cord / Int J Radiat Oncol Biol Phys 78:499~506
De Salles AA / 2004 / Spinal lesions treated with Novalis shaped beam intensity-modulated radiosurgery and stereotactic radiotherapy / J Neurosurg 101(Suppl 3):435~440
Bernstein EF / 1993 / Biology of chronic radiation effect on tissues and wound healing / Clin Plast Surg 20:435~453
Chang EL / 2007 / Phase I/II study of stereotactic body radiotherapy for spinal metastasis and its pattern of failure / J Neurosurg Spine 7:151~160
Choi CY / 2010 / Stereotactic radiosurgery for treatment of spinal metastases recurring in close proximity to previously irradiated spinal cord / Int J Radiat Oncol Biol Phys 78:499~506
De Salles AA / 2004 / Spinal lesions treated with Novalis shaped beam intensity-modulated radiosurgery and stereotactic radiotherapy / J Neurosurg 101(Suppl 3):435~440
이 논문의 저자 정보
최근 본 자료
댓글(0)
0