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자료유형
학술저널
저자정보
Choi, Eun Kyoung (Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea) Yoo, Ie Ryung (Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea) Park, Hye Lim (Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea) Choi, Hyun Su (Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea) Han, Eun Ji (Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea) Kim, Sung Hoon (Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea) Chung, Soo Kyo (Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea) O, Joo Hyun (Department of Radiology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea)
저널정보
대한핵의학회 Nuclear medicine and molecular imaging : NMMI Nuclear medicine and molecular imaging : NMMI 제46권 제3호
발행연도
2012.1
수록면
189 - 195 (7page)

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Purpose To assess the value of PET/CT for detecting local or distant recurrence in patients who undergo surgery for colorectal cancer (CRC) and to compare the accuracy of PET/CT to that of conventional imaging studies (CIS). Methods Tumor surveillance PET/CT scans done between March 2005 and December 2009 of disease-free patients after surgery with or without adjuvant chemotherapy for CRC were retrospectively studied. CIS (serial enhanced CT from lung base to pelvis and plain chest radiograph) were performed within 1 month of PET/CT. We excluded patients with distant metastasis on initial staging, a known recurrent tumor, and a lack of follow-up imaging. The final diagnosis was based on at least 6 months of follow-up with colonoscopy, biopsy, and serial imaging studies in combination with carcinoembryonic antigen levels. Results A total of 262 PET/CT scans of 245 patients were included. Local and distant recurrences were detected in 27 cases (10.3%). On case-based analysis, the overall sensitivity, specificity, and accuracy were 100, 97.0, and 97.3% for PET/CT and 85.1, 97.0, and 95.8% for CIS, respectively. On lesion-based analysis, PET/CT detected more lesions compared to CIS in local recurrence and lung metastasis. PET/CT and CIS detected the same number of lesions in abdominal lymph nodes, hepatic metastasis, and peritoneal carcinomatosis. PET/CT detected two more metachronous tumors than did CIS in the lung and thyroid gland. Conclusion PET/CT detected more recurrences in patients who underwent surgery for CRC than did CIS and had the additional advantage of evaluating the entire body during a single scan.

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