지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 533 - 542 (10page)
이용수
초록· 키워드
오류제보하기
We extracted essential oils from four species (Pinus densiflora, Larix kaempferi, Pinus koraiensis, and Abies holophylla) in the family Pinaceae to investigate their antibacterial activities against respiratory tract bacteria (Klebsiella pneumoniae, Haemophillus influenzae, Streptococcus pyogenes, Streptococcus pneumonia, and Neisseria meningitides). Among the tested oils, that from A. holophylla was showed strong activity based on disc diffusion and broth medium dilution (minimum inhibitory concentration, MIC) assays. Qualitative analysis of A. holophylla oil was carried out by GC-MS; ${\alpha}$-pinene, camphene, ${\beta}$-pinene, 3-carene, limonene, bornyl acetate, borneol, ${\beta}$-caryophyllene, ${\alpha}$-caryophyllene, caryophyllene oxide, and ${\alpha}$-bisabolol were identified as its major constituents. Fractionation by silica gel chromatography was performed to analyze the active constituents of the crude oil. In particular, one fraction containing caryophyllene oxide as the major constituent showed stronger antibacterial activity than the crude oil of A. holophylla. Growth rates of bacterial strains exposed to fraction D were explored by optical density (OD600) measurements while morphology was examined by optical microscopy observations ( ${\times}1000$). OD600 of K. pneumoniae decreased from 0.2582 to 0.005 in response to treatment with fraction D at a MIC value of $0.31{\mu}{\ell}/m{\ell}$.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
Bauernfeind, A. / 1999 / A novel type of AmpC β-lactamase, ACC-1, produced by a Klebsiella pneumoniae strain causing nosocomial pneumonia / Antimicrobial Agents and Chemotherapy 43(8):1924~1931
Corless, C. E. / 2001 / Simultaneous detection of Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae in suspected cases of meningitis and septicemia using real-time PCR / Journal of Clinical Microbiology 39(4):1553~1558
Fabio, A. / 2007 / Screening of the antibacterial effects of a variety of essential oils on microorganisms responsible for respiratory infections / Phytotherapy Research 21(4):374~377
Fritsche, T. R. / 2005 / Antimicrobial activity of tigecycline tested against organisms causing community-acquired respiratory tract infection and nosocomial pneumonia / Diagnostic Microbiology and Infectious Disease 52(3):187~193
Hüsnü, K. / 2007 / Flavours and Fragrances / Springer
Corless, C. E. / 2001 / Simultaneous detection of Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae in suspected cases of meningitis and septicemia using real-time PCR / Journal of Clinical Microbiology 39(4):1553~1558
Fabio, A. / 2007 / Screening of the antibacterial effects of a variety of essential oils on microorganisms responsible for respiratory infections / Phytotherapy Research 21(4):374~377
Fritsche, T. R. / 2005 / Antimicrobial activity of tigecycline tested against organisms causing community-acquired respiratory tract infection and nosocomial pneumonia / Diagnostic Microbiology and Infectious Disease 52(3):187~193
Hüsnü, K. / 2007 / Flavours and Fragrances / Springer
이 논문의 저자 정보
최근 본 자료
댓글(0)
0