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논문 기본 정보

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학술저널
저자정보
Kwon, Jang-Mi (Department of Pediatrics, Kangbuk Samsung Medical Center, Sungkyunkwan University School of Medicine) Shim, Jae Won (Department of Pediatrics, Kangbuk Samsung Medical Center, Sungkyunkwan University School of Medicine) Kim, Deok Soo (Department of Pediatrics, Kangbuk Samsung Medical Center, Sungkyunkwan University School of Medicine) Jung, Hye Lim (Department of Pediatrics, Kangbuk Samsung Medical Center, Sungkyunkwan University School of Medicine) Park, Moon Soo (Department of Pediatrics, Kangbuk Samsung Medical Center, Sungkyunkwan University School of Medicine) Shim, Jung Yeon (Department of Pediatrics, Kangbuk Samsung Medical Center, Sungkyunkwan University School of Medicine)
저널정보
대한소아청소년과학회 Clinical and Experimental Pediatrics Korean journal of pediatrics 제57권 제1호
발행연도
2014.1
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29 - 34 (6page)

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Purpose: In this study, we aimed to investigate the prevalence of year-round respiratory viral infection in children with lower respiratory tract infection (LRTI) and the relationship between respiratory viral infection and allergen sensitization in exacerbating asthma. Methods: We investigated the sources for acute LRTIs in children admitted to our hospital from May 2010 to April 2011. The 6 most common respiratory viruses were isolated from nasopharyngeal aspirate using multiplex reverse transcription-polymerase chain reaction in 309 children; respiratory syncytial virus (RSV), adenovirus (AV), parainfluenza virus (PIV), influenza virus (IFV), human metapneumovirus (hMPV), rhinovirus (RV). Atopic sensitization was defined if more than 1 serum specific Immunoglobulin E level measured using UniCAP (Pharmacia) was over 0.35 IU/mL. Results: RSV was the most common pathogen of bronchiolitis in hospitalized children through the year. RV or IFV infection was more prevalent in asthma exacerbations compared to other LRTIs. AV and hMPV were more likely to cause pneumonia. RV and IFV were associated with asthma exacerbations in children with atopic sensitization, but not in nonatopic children. Conclusion: RV and IFV are associated with hospitalization for asthma exacerbation in children with atopic sensitization.

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