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자료유형
학술저널
저자정보
Seo, Yu-Mi (Department of Pediatrics, College of Medicine, The Catholic University of Korea) Kang, Hyun-Mi (Department of Pediatrics, College of Medicine, The Catholic University of Korea) Lee, Sung-Churl (Department of Pediatrics, College of Medicine, The Catholic University of Korea) Yu, Jae-Won (Department of Pediatrics, Chungnam National University Hospital, School of Medicine, Chungnam National University) Kil, Hong-Ryang (Department of Pediatrics, Chungnam National University Hospital, School of Medicine, Chungnam National University) Rhim, Jung-Woo (Department of Pediatrics, College of Medicine, The Catholic University of Korea) Han, Ji-Whan (Department of Pediatrics, College of Medicine, The Catholic University of Korea) Lee, Kyung-Yil (Department of Pediatrics, College of Medicine, The Catholic University of Korea)
저널정보
대한소아청소년과학회 Clinical and Experimental Pediatrics Korean journal of pediatrics 제61권 제5호
발행연도
2018.1
수록면
160 - 166 (7page)

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Purpose: This study aimed to analyse laboratory values according to fever duration, and evaluate the relationship across these values during the acute phase of Kawasaki disease (KD) to aid in the early diagnosis for early-presenting KD and incomplete KD patients. Methods: Clinical and laboratory data of patients with KD (n=615) were evaluated according to duration of fever at presentation, and were compared between patients with and without coronary artery lesions (CALs). For evaluation of the relationships across laboratory indices, patients with a fever duration of 5 days or 6 days were used (n=204). Results: The mean fever duration was $6.6{\pm}2.3days$, and the proportions of patients with CALs was 19.3% (n=114). C-reactive proteins (CRPs) and neutrophil differential values were highest and hemoglobin, albumin, and lymphocyte differential values were lowest in the 6-day group. Patients with CALs had longer total fever duration, higher CRP and neutrophil differential values and lower hemoglobin and albumin values compared to patients without CALs. CRP, albumin, neutrophil differential, and hemoglobin values at the peak inflammation stage of KD showed positive or negative correlations each other. Conclusion: The severity of systemic inflammation in KD was reflected in the laboratory values including CRP, neutrophil differential, albumin, and hemoglobin. Observing changes in these laboratory parameters by repeated examinations prior to the peak of inflammation in acute KD may aid in diagnosis of early-presenting KD patients.

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