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자료유형
학술저널
저자정보
Seker, Mehmet Metin (Department of Medical Oncology, Cumhuriyet University Medical Faculty) Kos, Tugba (Department of Medical Oncology, Manisa State Hospital) Ozdemir, Nuriye (Department of Medical Oncology, Numune Education and Research Hospital) Seker, Ayse (Department of Medical Oncology, Mutki State Hospital) Aksoy, Sercan (Department of Medical Oncology, Hacettepe University Cancer Institute) Uncu, Dogan (Department of Medical Oncology, Numune Education and Research Hospital) Zengin, Nurullah (Department of Medical Oncology, Numune Education and Research Hospital)
저널정보
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제15권 제1호
발행연도
2014.1
수록면
327 - 330 (4page)

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Background: Ewing sarcoma is a small round cell tumor arising from soft tissue and bone that predominantly affects children and adolescents. The most unfavorable prognostic factor is the presence of distant metastasis at the time of diagnosis. Materials and Methods: The records of 26 Ewing sarcoma patients (14 male, 12 female) were re-evaluated retrospectively. Results: The median age was 26.5 (19-42) years. Eight patients (31%) showed a primary tumor in their extremities, 8 (31%) in the thorax, 4 (15%) at the vertebra, 4 (15%) in the head and neck, and 2 (8%) in the abdomen. Five patients (19%) had distant metastasis at diagnosis. The median progression-free survival was 72 months and 10 months in localized and metastatic disease, respectively (p=0.005). The overall survival rate was 19 months in metastatic disease, and the 5-year overall survival rate was 64% in localized disease (p=0.006). Patients who had localized disease in the extremities and were under age 30 had a favorable prognosis. Conclusions: Although Ewing sarcoma is a tumor affecting children and adolescents, it may be seen in adults, where the prognosis is generally worse. Although it is a highly malignant tumor, it is possible to achieve improved survival with combined modality treatments.

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