Association between Smoking and Mortality: Khon Kaen Cohort Study, Thailand

Kamsa-ard, Siriporn; Promthet, Supannee; Lewington, Sarah; Burrett, Julie Ann; Sherliker, Paul; Kamsa-ard, Supot; Wiangnon, Surapon; Parkin, Donald Maxwell

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자료유형: 학술저널

저자정보: Kamsa-ard, Siriporn (Department of Biostatistics and Demography, Faculty of Medicine, Khon Kaen University) Promthet, Supannee (Department of Epidemiology, Faculty of Public Health, Khon Kaen University) Lewington, Sarah (Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford) Burrett, Julie Ann (Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford) Sherliker, Paul (Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford) Kamsa-ard, Supot (Cancer Unit, Faculty of Medicine, Khon Kaen University) Wiangnon, Surapon (Department of Pediatrics, Faculty of Medicine, Khon Kaen University) Parkin, Donald Maxwell (Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제14권 제4호

발행연도: 2013.1

수록면: 2,643 - 2,647 (5page)

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Background: Despite anti-smoking campaigns, smoking prevalence among Thai males aged 30 or older is high, at around 50%. The purpose of this study was to determine the relationship between smoking and mortality in a rural Thai community. Materials and Methods: Subjects enrolled into the Khon Kaen cohort study between 1990 and 2001 were followed up for their vital status until $16^{th}$ March 2012. The death resource was from the Bureau of Policy and Strategy, Ministry of Interior, Thailand. A Cox proportional hazards model was used to analyse the association between smoking and death, controlling for age, education level and alcohol drinking, and confidence intervals were calculated using the floating risk method. Results: The study recruited 5,962 male subjects, of whom 1,396 died during a median 13.5 years of follow-up. Current smokers were more likely to die than never smokers after controlling for age, education level and alcohol drinking (HR, 95%CI: 1.41, 1.32-1.51), and the excess mortality was greatest for lung cancer (HR, 95%CI: 3.51, 2.65-4.66). However, there was no increased risk with increasing dose of tobacco, and no difference in risk between smokers of yamuan (hand-rolled cigarettes) and manufactured tobacco. Conclusion: Mortality from cancer, particularly lung cancer, and from all causes combined is dependent on smoking status among men in rural Thailand, but the relative risks are lower than have been reported from studies in high income countries, where the tobacco epidemic is more established.

#Smoking #mortality #health behaviour #rural population #Thai males

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Kamsa-ard, Siriporn

소속기관 Department of Epidemiology and Biostatistics, Faculty of Public Health, Khon Kaen University