Use of Blood Transfusion at the End of Life: Does it Have Any Effects on Survival of Cancer Patients?

Goksu, Sema Sezgin; Gunduz, Seyda; Unal, Dilek; Uysal, Mukremin; Arslan, Deniz; Tatli, Ali Murat; Bozcuk, Hakan; Ozdogan, Mustafa; Coskun, Hasan Senol

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자료유형: 학술저널

저자정보: Goksu, Sema Sezgin (Department of Medical Oncology, Kayseri State Hospital of Research and Education) Gunduz, Seyda (Department of Medical Oncology, Akdeniz University, Faculty of Medicine) Unal, Dilek (Department of Radiation Oncology, Kayseri State Hospital of Research and Education) Uysal, Mukremin (Department of Medical Oncology, Akdeniz University, Faculty of Medicine) Arslan, Deniz (Department of Medical Oncology, Akdeniz University, Faculty of Medicine) Tatli, Ali Murat (Department of Medical Oncology, Akdeniz University, Faculty of Medicine) Bozcuk, Hakan (Department of Medical Oncology, Akdeniz University, Faculty of Medicine) Ozdogan, Mustafa (Department of Medical Oncology, Akdeniz University, Faculty of Medicine) Coskun, Hasan Senol (Department of Medical Oncology, Akdeniz University, Faculty of Medicine)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제15권 제10호

발행연도: 2014.1

수록면: 4,251 - 4,254 (4page)

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Background: Treatment of anemia is an important issue in the palliative care setting. Blood transfusion is generally used for this purpose in supportive care. However the place of blood transfusion in terminally ill cancer cases is less far established. Objective: We aimed to outline the use of transfusions and to find the impact of blood transfusion on survival in patients with advanced cancer and very near to death. Design: Patients dying in 2010-2011 with advanced cancer were included in the study. We retrospectively collected the data including age, type of cancer, the duration of last hospitalisation, ECOG performance status, Hb levels, transfusion history of erythrocytes and platelets, cause and the amount of transfusion. The anaemic patients who had transfusion at admission were compared with the group who were not transfused. Survival was defined as the time between the admission of last hospitalisation period and death. Results: Three hundred and ninety eight people with solid tumours died in 2010-2011 in our clinic. Ninety percent of the patients had anemia at the time of last hospitalisation. One hundred fifty three patients had erythrocyte transfusion at admission during the last hospitalisation period (38.4%). In the anaemic population the duration of last hospitalisation was longer in patients who had erythrocyte transfusion (15 days vs 8 days, p<0.001). Conclusions: Patients who had blood transfusion at the end of life lived significantly longer than the anaemic patients who were not transfused. This study remarks that blood transfusions should not be withheld from terminal cancer patients in palliative care.

#Blood tansfusion #terminally ill cancer

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