Evaluation of Environmental Risk Factors for Prostate Cancer in a Population of Iranian Patients

Pouresmaeili, Farkhondeh; Hosseini, S. Jalil; Farzaneh, Farah; Karimpour, Arezoo; Azargashb, Eznollah; Yaghoobi, Mohammad; Kamarehei, Maryam

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저자정보: Pouresmaeili, Farkhondeh (Department of Medical Genetics and Infertility and Reproductive Health Research Center, Faculty of Medicine, Shahid Beheshti University of Medical Sciences) Hosseini, S. Jalil (Infertility and Reproductive Health Research Center, Faculty of Medicine, Shahid Beheshti University of Medical Sciences) Farzaneh, Farah (Department of Obstetrics and Gynecology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences) Karimpour, Arezoo (Department of Medical Genetics and Infertility and Reproductive Health Research Center, Faculty of Medicine, Shahid Beheshti University of Medical Sciences) Azargashb, Eznollah (Department of Community Medicine, Faculty of Medicine, Shahid Beheshti University of Medical Sciences) Yaghoobi, Mohammad (Urology Department, Faculty of Medicine, Shahid Beheshti University of Medical Sciences) Kamarehei, Maryam (Institute of Biochemistry and Biophysics, University of Tehran)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제15권 제24호

발행연도: 2014.1

수록면: 10,603 - 10,605 (3page)

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Background: The Prostate cancer is the 2nd most common cancer worldwide for males, and the 5th most common cancer overall, with an estimated 900,000 new cases diagnosed in 2008 (14% of the total in males and 7% of the total overall) aim of this study was to assess some of the most proposed environmental factors influencing the incidence of prostate cancer among Iranian men. Smoking, opioids, occupation and living location were considered as studied risk factors of the prostate cancer in this research. Material and methods: Two groups of affected men with prostate cancer and controls aged 50-75 years referred to medical clinics were subjects in this case-control study. Living and working place, smoking and drug consuming habits were assessed for any associations with prostate cancer. Results: The largest number, of patients, in order, belonged to Tehran, provincial capitals, major industrial cities, small towns and villages, respectively. The disease showed links with smoking and drugs with a significant difference between controls and patients (P value <0.0001). Conclusions: Our recent evidence duplicates previously done researches confirming the serious adverse effects of smoking and drugs on the prostate cancer occurrence in Iranian men. Living place bearings some hazardous behaviors which increases the rate of diseases as well as advanced chance for associated cancers like prostate.

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Pouresmaeili, Farkhondeh

소속기관 Department of Medical Genetics and Infertility and Reproductive Health Research Center, Faculty of M