Distinct Postsurgical Management in Young and Elderly Breast Cancer Patients Results in Equal Survival Rates

Oran, Ebru Sen; Yankol, Yucel; Soybir, Gursel Remzi; Karsidag, Tamer; Sakalli, Onur; Gecgel, Umit; Soybir, Onur Can; Soran, Atilla

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자료유형: 학술저널

저자정보: Oran, Ebru Sen (Department of General Surgery, Bakirkoy Research and Training State Hospital) Yankol, Yucel (Department of General Surgery, Bakirkoy Research and Training State Hospital) Soybir, Gursel Remzi (Department of General Surgery, Medical Faculty, Namik Kemal University) Karsidag, Tamer (Department of General Surgery, Atasehir Memorial Hospital) Sakalli, Onur (Department of General Surgery, Medical Faculty, Namik Kemal University) Gecgel, Umit (Department of General Surgery, Medical Faculty, Namik Kemal University) Soybir, Onur Can (Premed Section, Art of Sciences) Soran, Atilla (Department of Breast Surgery, Magge Womens Hospital, University of Pittsburgh)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제15권 제18호

발행연도: 2014.1

수록면: 7,843 - 7,847 (5page)

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Background: Although breast cancer (BC) is one of the most common malignant diseases in women, the majority of the studies describing the characteristics of BC in elderly patients have been limited to survival assessments or tumor features, without using younger BC patients as a reference group. The aim of our study was to describe and compare tumor characteristics and management patterns in elderly versus younger breast cancer patients in Turkey. Materials and Methods: We retrospectively analyzed 152 patients with invasive breast cancer who underwent surgery in our institution between 2002 and 2012. Patients were divided into 2 groups according to age at the time of diagnosis. Results: There were 62 patients in the elderly group (${\geq}65$ years) and 90 patients in the younger group (<65 years). Compared to the younger group, tumors in the elderly group were more likely to be larger (p=0.018), of lower grade (p=0.005), and hormone receptor-positive (p>0.001). There were no significant differences regarding histology, localization, lymph node involvement, or types of surgical procedures between the 2 groups. Comorbidities were more common in elderly patients (p<0.001). In addition, elderly patients were more likely to receive hormonal therapy (p<0.001) and less likely to receive radiotherapy (p=0.08) and chemotherapy (p=0.003). There was no difference in survival and locoregional recurrence rates between the groups. Conclusions: The results of this study demonstrate that breast cancer in elderly patients has more favorable tumor features, warranting less aggressive treatment regimens after surgery.

#Breast cancer #elderly #survival #recurrence

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