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Ghosh, Saptarshi (Department of Radiation Oncology, GSL Medical College and General Hospital) Sarkar, Shreyasee (Department of Pathology, GSL Medical College and General Hospital) Simhareddy, Samara (Department of Community Medicine, GSL Medical College and General Hospital) Kotne, Sivasankar (Department of Radiation Oncology, GSL Medical College and General Hospital) Rao, Pammidimukkala Bramh Ananda (Department of Radiation Oncology, GSL Medical College and General Hospital) Turlapati, Satya Prakash Venkatachalam (Department of Pathology, GSL Medical College and General Hospital)
저널정보
아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제15권 제18호
발행연도
2014.1
수록면
7,839 - 7,842 (4page)

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Background: Breast cancer is the most common malignancy in women worldwide and the second most common cancer in females in India. Receptor status may be important for survival. Objective: To analyse and correlate the clinical and morphological parameters with receptor status in breast carcinoma patients in a tertiary care institution in Southern India. Materials and Methods: This retrospective study involved 320 patients of breast cancer diagnosed in an oncology hospital over a period of $3^{1/2}$ years. Data was analysed using SPSS Version 21. Results: Some 60.6% patients with breast carcinomas belonged to the age group of 40 to 60 years. The most common histological type was infiltrating ductal carcinoma, not otherwise specified, accounting for 84.4% of patients. On immunohistochemistry, estrogen receptor (ER) and progesterone receptor (PR) were expressed in 56.3% and 53.1% of cases, respectively. Conclusions: Breast cancers in India, a developing country, occur in younger women and tend to be more aggressive with lower rates of ER and PR expression and higher histological tumor grades. Both ER and PR status of the tumors had significant associations with the patient age, pathological TNM stage and histological tumor grade.

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