Lack of Any Relationship between ABO and Rh Blood Groups and Clinicopathological Features in Patients with Gastrointestinal Stromal Tumors: Turkish Oncology Group

Urun, Yuksel; Utkan, Gungor; Yalcin, Suayib; CosKun, Hasan Senol; Kocer, Murat; Ozdemir, Nuriye Yildirim; Kaplan, Mehmet Ali; Arslan, Ulku Yalcintas; Ozdemir, Feyyaz; Oztuna, Derya; Akbulut, Hakan; Icli, Fikri

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자료유형: 학술저널

저자정보: Urun, Yuksel (Faculty of Medicine, Ankara University) Utkan, Gungor (Faculty of Medicine, Ankara University) Yalcin, Suayib (Faculty of Medicine, Hacettepe University) CosKun, Hasan Senol (Faculty of Medicine, Akdeniz University) Kocer, Murat (Faculty of Medicine, Suleyman Demirel University) Ozdemir, Nuriye Yildirim (Ankara Numune, Research and Educational Hospital) Kaplan, Mehmet Ali (Faculty of Medicine, Dicle University) Arslan, Ulku Yalcintas (Medical Oncology Clinic, Ankara Oncology, Research and Educational Hospital) Ozdemir, Feyyaz (Department of Medical Oncology, Faculty of Medicine, Karadeniz Tecnichal University) Oztuna, Derya (Department of Biostatistics, Faculty of Medicine, Ankara University Turkey) Akbulut, Hakan (Faculty of Medicine, Ankara University) Icli, Fikri (Faculty of Medicine, Ankara University)

저널정보: 아시아태평양암예방학회 Asian Pacific journal of cancer prevention : APJCP Asian Pacific journal of cancer prevention : APJCP 제13권 제8호

발행연도: 2012.1

수록면: 4,129 - 4,131 (3page)

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Background: An association between the ABO blood group and the risk of certain malignancies, including pancreatic and gastric cancer, has been reported previously. However, it is unclear whether this association is valid for gastrointestinal stromal tumors (GIST). In this study, ABO blood groups and the Rh factor were investigated in a series of GIST cases. Material and Methods: In 162 patients with GIST, blood group and Rh factor were examined and compared with a control group of 3,022,883 healthy volunteer blood donors of the Turkish Red Crescent between 2004 and 2011. The relationship of blood groups with tumor size, mitotic activity, and age were also evaluated. Results: Overall, the ABO blood group and Rh factor distributions of the 162 patients with GIST were similar to those of the general population. There were no significant differences between both ABO blood types and Rh factor in terms of tumor size, mitotic activity, and age. Conclusion: This is the first study reported on this issue. In our study, we didn't find any relationship between GIST and ABO blood group and Rh factor. However further studies with larger number of patients are needed to establish the role of blood groups in this population.

#Gastrointestinal stromal tumor #ABO blood group #Rh factor #Turkey

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