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논문 기본 정보

자료유형
학술저널
저자정보
Guerard, Sandra (Institut de Biomecanique Humaine George Charpak, Arts et Metiers ParisTech) Manassero, Mathieu (Ecole Nationale Veterinaire d'Alfort, Service de Chirurgie) Viateau, Veronique (Ecole Nationale Veterinaire d'Alfort, Service de Chirurgie) Migonney, Veronique (Universite Paris 13, Laboratoire de Biomateriaux et Polymeres de Specialite/CSPBAT, UMR CNRS 7244) Skalli, Wafa (Institut de Biomecanique Humaine George Charpak, Arts et Metiers ParisTech) Mitton, David (Institut de Biomecanique Humaine George Charpak, Arts et Metiers ParisTech)
저널정보
테크노프레스 Advances in biomechanics & applications Advances in biomechanics & applications 제1권 제4호
발행연도
2014.1
수록면
239 - 252 (14page)

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This study aimed to assess the biomechanical performance of a new generation of artificial ligament, which can be considered "bioactive" and "biointegrated," implanted in sheep. Thirty sheep were implanted: 15 sheep received the artificial ligament grafted with a bioactive polymer (grafted) and 15 received the artificial ligament without a bioactive polymer (non-grafted). The animals were sacrificed 3 or 12 months after implantation. The knee kinematics, namely flexion-extension, anterior drawer, and varus-valgus tests, were evaluated using a fully characterized custom-made device. Afterward, the specimens were tested under uniaxial tension until failure. The flexion-extension showed significant differences between (grafted or non-grafted) artificial and native ligaments 3 months after implantation. This difference became non-significant 12 months postoperatively. The anterior tibial drawer was significantly increased 3 months after implantation and remained significantly different only for non-grafted ligament 12 months after implantation. Twelve months after implantation, the differences between grafted and non-grafted ligament biomechanical properties were significant in terms of stiffness. In terms of load to failure, grafted ligaments seem to have had slightly better performance than non-grafted ligaments 12 months postoperatively. Overall these results suggest that grafted artificial ligaments have slightly better biomechanical characteristics than non-grafted artificial ligaments 12 months after implantation in sheep.

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