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자료유형
학술저널
저자정보
Jeong, Seong-Il (Department of Microbiology, School of Medicine, Kyung Hee University) Lee, Seung-Eun (Department of Microbiology, School of Medicine, Kyung Hee University) Yang, Ha-Na (Department of Microbiology, School of Medicine, Kyung Hee University) Jin, Young-Ho (Department of Physiology, School of Medicine, Kyung Hee University) Park, Cheung-Seog (Department of Microbiology, School of Medicine, Kyung Hee University) Park, Yong-Seek (Department of Microbiology, School of Medicine, Kyung Hee University)
저널정보
대한독성유전단백체학회 Molecular & cellular toxicology Molecular & cellular toxicology 제6권 제4호
발행연도
2010.1
수록면
373 - 380 (8page)

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Compared to plant cellulose, bacterial cellulose synthesized by Gluconacetobacter xylinus has features such as high crystallinity, tensile strength and water absorption capacity; biocompatibility; resistance to degradation and low solubility that may be advantageous for engineered tissue. However, little information is available concerning the potential toxicity of bacterial cellulose-based biomaterials. The present study investigated the toxicity of bacterial cellulose nanofibers in vitro in human umbilical vein endothelial cells (HUVECs) using viability and flow cytometric assays and in vivo using C57/Bl6 mice. The absence of toxicity in vitro and in vivo supports the view that bacterial cellulose may be amenable for use as a tissue engineering biomaterial.

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