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논문 기본 정보

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학술저널
저자정보
Sung, Ha-Min (Department of Plastic and Reconstructive Surgery, Kangnam Sacred Heart Hospital, Hallym University Medical Center) Suh, In-Suck (Department of Plastic and Reconstructive Surgery, Kangnam Sacred Heart Hospital, Hallym University Medical Center) Lee, Hoon-Bum (Department of Plastic and Reconstructive Surgery, Kangnam Sacred Heart Hospital, Hallym University Medical Center) Tak, Kyoung-Seok (Department of Plastic and Reconstructive Surgery, Kangnam Sacred Heart Hospital, Hallym University Medical Center) Moon, Kyung-Min (Department of Plastic and Reconstructive Surgery, Kangnam Sacred Heart Hospital, Hallym University Medical Center) Jung, Min-Su (Department of Plastic and Reconstructive Surgery, Kangnam Sacred Heart Hospital, Hallym University Medical Center)
저널정보
대한성형외과학회 Archives of plastic surgery : APS Archives of plastic surgery : APS 제39권 제1호
발행연도
2012.1
수록면
51 - 54 (4page)

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With the gradual increase of cases using fillers, cases of patients treated by non-medical professionals or inexperienced physicians resulting in complications are also increasing. We herein report 2 patients who experienced acute complications after receiving filler injections and were successfully treated with adipose-derived stem cell (ADSCs) therapy. Case 1 was a 23-year-old female patient who received a filler (Restylane) injection in her forehead, glabella, and nose by a non-medical professional. The day after her injection, inflammation was observed with a $3{\times}3cm$ skin necrosis. Case 2 was a 30-year-old woman who received a filler injection of hyaluronic acid gel (Juvederm) on her nasal dorsum and tip at a private clinic. She developed erythema and swelling in the filler-injected area A solution containing ADSCs harvested from each patient's abdominal subcutaneous tissue was injected into the lesion at the subcutaneous and dermis levels. The wounds healed without additional treatment. With continuous follow-up, both patients experienced only fine linear scars 6 months postoperatively. By using adipose-derived stem cells, we successfully treated the acute complications of skin necrosis after the filler injection, resulting in much less scarring, and more satisfactory results were achieved not only in wound healing, but also in esthetics.
#Hyaluronic acid #Humans #Mesenchymal stem cell transplantation #Necrosis

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참고문헌 (8)

참고문헌 신청
Utsunomiya T / 2011 / Human adiposederived stem cells: potential clinical applications in surgery / Surg Today 41:18~23 google schola Klein AW / 2000 / The history of substances for soft tissue augmentation / Dermatol Surg 26:1096~1105 google schola Weinberg MJ / 2009 / Complications of hyaluronic acid fillers / Facial Plast Surg 25:324~328 google schola Grunebaum LD / 2009 / The risk of alar necrosis associated with dermal filler injection / Dermatol Surg 35(Suppl 2):1635~1640 google schola Brody HJ / 2005 / Use of hyaluronidase in the treatment of granulomatous hyaluronic acid reactions or unwanted hyaluronic acid misplacement / Dermatol Surg 31:893~897 google schola

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