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자료유형
학술저널
저자정보
Talibov, Madar (Faculty of Social/Health Sciences, University of Tampere) Sormunen, Jorma (Faculty of Social/Health Sciences, University of Tampere) Weiderpass, Elisabete (Department of Community Medicine, Faculty of Health Sciences, University of Tromso, The Arctic University of Norway) Kjaerheim, Kristina (Cancer Registry of Norway) Martinsen, Jan-Ivar (Cancer Registry of Norway) Sparen, Per (Department of Medical Epidemiology and Biostatistics, Karolinska Institutet) Tryggvadottir, Laufey (Icelandic Cancer Registry) Hansen, Johnni (The Danish Cancer Society Research Center) Pukkala, Eero (Faculty of Social/Health Sciences, University of Tampere)
저널정보
산업안전보건연구원 Safety and health at work : SH@W Safety and health at work : SH@W 제10권 제2호
발행연도
2019.1
수록면
141 - 150 (10page)

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Background: Evidence on associations between occupational diesel exhaust and gasoline exposure and colorectal cancer is limited. We aimed to assess the effect of workplace exposure to diesel exhaust and gasoline on the risk of colorectal cancer. Methods: This case-control study included 181,709 colon cancer and 109,227 rectal cancer cases diagnosed between 1961 and 2005 in Finland, Iceland, Norway, and Sweden. Cases and controls were identified from the Nordic Occupational Cancer Study cohort and matched for country, birth year, and sex. Diesel exhaust and gasoline exposure values were assigned by country-specific job-exposure matrices. Odds ratios and 95% confidence intervals were calculated by using conditional logistic regression models. The results were adjusted for physical strain at work and occupational exposure to benzene, formaldehyde, ionizing radiation, chlorinated hydrocarbons, chromium, and wood dust. Results: Diesel exhaust exposure was associated with a small increase in the risk of rectal cancer (odds ratio - 1.05, 95% confidence interval 1.02-1.08). Gasoline exposure was not associated with colorectal cancer risk. Conclusion: This study showed a small risk increase for rectal cancer after workplace diesel exhaust exposure. However, this finding could be due to chance, given the limitations of the study.

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