Effect of Biopsy Technique on the Survival Rate of Malignant Melanoma Patients

Yamashita, Yutaro; Hashimoto, Ichiro; Abe, Yoshiro; Seike, Takuya; Okawa, Katsumasa; Senzaki, Yuichi; Murao, Kazutoshi; Kubo, Yoshiaki; Nakanishi, Hideki

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저자정보: Yamashita, Yutaro (Departments of Plastic and Reconstructive Surgery and Dermatology, The University of Tokushima Graduate School) Hashimoto, Ichiro (Departments of Plastic and Reconstructive Surgery and Dermatology, The University of Tokushima Graduate School) Abe, Yoshiro (Departments of Plastic and Reconstructive Surgery and Dermatology, The University of Tokushima Graduate School) Seike, Takuya (Departments of Plastic and Reconstructive Surgery and Dermatology, The University of Tokushima Graduate School) Okawa, Katsumasa (Departments of Plastic and Reconstructive Surgery and Dermatology, The University of Tokushima Graduate School) Senzaki, Yuichi (Departments of Plastic and Reconstructive Surgery and Dermatology, The University of Tokushima Graduate School) Murao, Kazutoshi (Departments of Plastic and Reconstructive Surgery and Dermatology, The University of Tokushima Graduate School) Kubo, Yoshiaki (Departments of Plastic and Reconstructive Surgery and Dermatology, The University of Tokushima Graduate School) Nakanishi, Hideki (Departments of Plastic and Reconstructive Surgery and Dermatology, The University of Tokushima G)

저널정보: 대한성형외과학회 Archives of plastic surgery : APS Archives of plastic surgery : APS 제41권 제2호

발행연도: 2014.1

수록면: 122 - 125 (4page)

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Background Cutaneous malignant melanoma has a poor prognosis. The detrimental effect of incisional biopsies on the outcome of malignant melanoma has been debated. The aim of this study was to determine the effect of the presence and type of biopsy on the prognosis of malignant melanoma. Methods The medical records of 109 malignant melanoma patients treated at Tokushima University Hospital from 1983 to 2007 were reviewed. After excluding 28 cases with stage 0 disease or incomplete data, 81 cases were analyzed in detail with respect to patient sex, age, tumor site, clinical stage at diagnosis, presence of ulceration or lymph node metastasis, and prognosis. The five-year survival and five-year disease-free survival rates of patients who underwent incisional or excisional biopsies were compared with those who did not undergo a biopsy. Results The male-to-female ratio was 1:1.19. The mean age was 61.3 years (range, 19-93 years). The most common site was a lower extremity, and the most common clinical stage was stage II. No significant differences in clinicopathological features, five-year survival rates, and five-year disease-free survival rates were observed among the three groups. Conclusions The presence and type of biopsy neither affected the metastatic rate nor the prognosis of malignant melanoma. The use of incisional biopsies is not encouraged because tumor thickness cannot be measured accurately. However, they may be helpful for confirming the diagnosis if an excisional biopsy cannot be performed.

#Melanoma #Prognosis #Survival rate

참고문헌 (10)

참고문헌 신청

Ishihara K / 2008 / Statistical profiles of malignant melanoma and other skin cancers in Japan: 2007update / Int J Clin Oncol 13:33~41

Karjalainen S / 1988 / Survival and prognostic factors of patients with skin melanoma: a regression-model analysis based on nationwide cancer registry data / Cancer 62:2274~2280

Leiter U / 2012 / Hazard rates for recurrent and secondary cutaneous melanoma: an analysis of 33,384 patients in the German Central Malignant Mela-noma Registry / J Am Acad Dermatol 66:37~45

Sobin LH / 2009 / TNM clas-sification of malignant tumours / Wiley-Blackwell

Rampen FH / 1980 / Incisional proce-dures and prognosis in malignant melanoma / Clin Exp Der-matol 5:313~320

이 논문의 저자 정보

Yamashita, Yutaro

소속기관 Department of Plastic and Reconstructive Surgery, Tokushima University Graduate School of Medical Sc

주요연구분야 의약학 > 임상의학 > 성형외과학

논문수 2 이용수 0

Hashimoto, Ichiro

소속기관 Department of Plastic and Reconstructive Surgery, Tokushima University Graduate School of Medical Sc

주요연구분야 의약학 > 임상의학 > 성형외과학

논문수 3 이용수 0

Abe, Yoshiro

소속기관 Department of Plastic and Reconstructive Surgery, Tokushima University Graduate School of Medical Sc

주요연구분야 의약학 > 임상의학 > 성형외과학

논문수 3 이용수 0

Seike, Takuya