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자료유형
학술저널
저자정보
Baik, Bong Soo (Department of Plastic and Reconstructive Surgery, Dong-Kang General Hospital) Lee, Wu Seop (Department of Plastic and Reconstructive Surgery, Dong-Kang General Hospital) Ji, So Young (Department of Plastic and Reconstructive Surgery, Dong-Kang General Hospital) Park, Ki Sung (Department of Plastic and Reconstructive Surgery, Dong-Kang General Hospital) Yang, Wan Suk (Department of Plastic and Reconstructive Surgery, Dong-Kang General Hospital) Kim, Sun Young (Department of Pathology, Dong-Kang General Hospital)
저널정보
대한두개안면성형외과학회 Archives of craniofacial surgery : ACFS Archives of craniofacial surgery : ACFS 제20권 제3호
발행연도
2019.1
수록면
207 - 211 (5page)

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Primary cutaneous anaplastic large cell lymphoma (C-ALCL) is a rare subtype of primary cutaneous lymphoma with a favorable prognosis. Primary cutaneous CD30+ lymphoproliferative disorders, which include C-ALCL and lymphomatoid papulosis, are the second most common group of cutaneous T-cell lymphomas. C-ALCL is comprised of large cells with anaplastic, pleomorphic, or immunoblastic cytomorphology, and indeed, more than 75% of the tumor cells express the CD30 antigen. C-ALCL clinically presents with solitary or localized reddish-brown nodules or tumors, and sometimes indurated papules, and they may be with ulceration covering with dark eschar. Multifocal lesions are seen in 20% of the patients. Extracutaneous dissemination, which mainly involves the regional lymph nodes, occurs in 10% of patients. A 69-year-old man noticed a mild elevated cutaneous lesion containing central ulceration covering with brownish black necrotic tissue on the right lower lip, and the lesion was surgically removed. After the first operation, another skin lesion was developed and the histological examination confirmed the diagnosis, C-ALCL. Eight specimens were excised during the 7-month follow-up period. The patient started the treatment with low-dose oral methotrexate (15 mg/wk) and there was no recurrence for 11 months.

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