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자료유형
학술저널
저자정보
Moon, Sun- Hee (Division of Animal Life Science, Konkuk University) Lee, Kyoung-Ah (Division of Animal Life Science, Konkuk University) Park, Keun-Kyu (Division of Animal Life Science, Konkuk University) Kim, Kee-Tae (Bio/Molecular Informatics Center, Konkuk University) Park, Yong-Sun (Bio/Molecular Informatics Center, Konkuk University) Nah, Seung-Yeal (Bio/Molecular Informatics Center, Konkuk University) Mendonca, Aubrey F. (Department of Food Science and Human Nutrition, Iowa State University) Paik, Hyun-Dong (Division of Animal Life Science, Konkuk University)
저널정보
한국축산식품학회 한국축산식품학회지 한국축산식품학회지 제31권 제3호
발행연도
2011.1
수록면
413 - 419 (7page)

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The antimicrobial effects of the natural flavonoids kaempferol, quercetin, apigenin, and naringenin as well as a novel flavonoid 7-O-butyl naringenin against the growth of four meat-born Staphylococcus aureus strains were evaluated. First, the flavonoids were screened for inhibitory effects against the growth of each strain using the paper disc diffusion method. Second, the growth inhibitory effects of flavonoids that showed antimicrobial activity were measured using the microplate method. Third, the bactericidal effects of flavonoids were evaluated in a 0.8% (w/v) NaCl solution. All flavonoids showed bacteriostatic effects at >20 mM. Among the flavonoids studied, quercetin was more effective than the others tested. However, the inhibitory effect of 7-O-butyl naringenin on growth of S. aureus KCCM 32395 was greater than that of quercetin at the same concentration. Additionally, 7-O-butyl naringenin exhibited significant bactericidal effects at >25 ${\mu}M$. When bacterial cells were examined using scanning electron microscopy, it appeared that the S. aureus membranes were damaged or morphologically changed when treated with quercetin and 7-O-butyl naringenin at 200 ${\mu}M$.

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