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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.4
- 수록면
- 95 - 95 (1page)
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A specific DNA conjugated to an active protein is not only used to identify, manipulate and functionalize the protein but also, in itself, a programmable linker that can connect the protein to other molecules. However, maintaining a protein activity after the conjugation remains as a critical issue. In this work, we propose the use of guanine analogue for the aptamer-directed covalent conjugation of DNA to an unmodified protein. The guanine analogue, formed by nitrosation of guanine, is able t ... 전체 초록 보기
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