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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.4
- 수록면
- 79 - 79 (1page)
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Immunoassay has been one of key technologies for determination of biomarkers in complex biological fluids such as blood, urine, and saliva. Enzyme-linked immunosorbent assay (ELISA), which is the most widely used immunoassay technique, is the gold standard for quantitative analysis of protein biomarkers. However, it takes several hours of analysis, and requires huge and expensive instruments as well as intervention of experts. Rapid diagnostic test (RDT), which is based on lateral flow immunoassay (LFIA), allows low-cost, rapid detection of biomarkers. However, it is neither accurate nor precise, thus usually applied for qualitative screening of non-critical biomarkers. Recently, bench-top immunoassay systems based on microfluidics and fluorescence have been introduced to the market. They are more precise than RDT, but require expensive optical components sensitive to dusts and vibration, as well as additional steps with external instruments for sample preparation. Therefore, the commercial bench-top systems are not appropriate for the point-of-care testing and self-monitoring of dis ... 전체 초록 보기
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