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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.3
- 수록면
- 130 - 130 (1page)
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Introduction and Background
To evaluate the altered gene and protein expression patterns in the rotator cuff muscles of the patients with rotator cuff tears who got frequent corticosteroid joint injection compared with those who had no history of corticosteroid injection.
Material and Method
Twenty-four samples of rotator cuff muscle from 12 patients with frequent corticosteroid joint injection history (steroid (+) group: 7 men and 5 women; mean age 63.0±7.2 years) and age- and sex-matched 12 control patients without steroid injection history (steroid (-) group: 7 men and 5 women; mean age 62.8±7.7 years) with medium-sized tears were acquired during arthroscopic surgery. As a statistical method, the propensity score matching technique was used to select control group by 1:1 matching for age and gender. Inclusion criteria were patients that underwent arthroscopic repair for medium-sized full-thickness rotator cuff tears and had history of frequent steroid injection (more than 5 times of steroid joint injection including more than once within recent 3 months). Patients lacking medium-sized tears, isolated subscapularis tear, preoperative stiff shoulder, acute traumatic tear, current heavy smoker (>20 pack year), uncontrolled diabetes, or previous surgery on the same shoulder, or those that declined to participate were excluded. Alterations in the expression of genes and proteins associated w ... 전체 초록 보기
To evaluate the altered gene and protein expression patterns in the rotator cuff muscles of the patients with rotator cuff tears who got frequent corticosteroid joint injection compared with those who had no history of corticosteroid injection.
Material and Method
Twenty-four samples of rotator cuff muscle from 12 patients with frequent corticosteroid joint injection history (steroid (+) group: 7 men and 5 women; mean age 63.0±7.2 years) and age- and sex-matched 12 control patients without steroid injection history (steroid (-) group: 7 men and 5 women; mean age 62.8±7.7 years) with medium-sized tears were acquired during arthroscopic surgery. As a statistical method, the propensity score matching technique was used to select control group by 1:1 matching for age and gender. Inclusion criteria were patients that underwent arthroscopic repair for medium-sized full-thickness rotator cuff tears and had history of frequent steroid injection (more than 5 times of steroid joint injection including more than once within recent 3 months). Patients lacking medium-sized tears, isolated subscapularis tear, preoperative stiff shoulder, acute traumatic tear, current heavy smoker (>20 pack year), uncontrolled diabetes, or previous surgery on the same shoulder, or those that declined to participate were excluded. Alterations in the expression of genes and proteins associated w ... 전체 초록 보기
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