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- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.7
- 수록면
- 169 - 169 (1page)
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Chronic pruritus is a symptom that reduces the quality of life of patients with inflammatory skin disease. Persistent activation of astrocytic signal transducer and activator of transcription 3 (STAT3) contributes to the elevation of chronic pruritus. STAT3 activation increases lipocalin-2 (LCN2) expression and enhances pruritus. A 2,3-dehydrosilybin (DHS) is a type of flavonoid extracted from the seeds of milk thistle. DHS has been reported to have hepatoprotective, angiogenic, and antioxidant effects. In this study, the inhibitory effect of DHS on ch ... 전체 초록 보기
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