지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
Purpose: This meta-analysis was conducted to analyze the effect of Diabetes Mellitus (DM) on the risk of Parkinson Disease (PD). Methods: Original prospective observational studies were searched through PubMed, Cumulative Index of Nursing and Allied Health Literature (CINAHL), ProQuest, Web of Science, Science Direct, Koreanstudies Information Service System (KISS), and DBpia published up to March 2020. The Relative Risks (RRs) were calculated using the random-effects model. Results: An integrated analysis of ten large population-based cohort studies, involving 10,730,117 participants, showed that patients with DM had a 30% higher risk of PD than those without DM (pooled RR=1.30, 95% Confidence Interval [CI]=1.14~1.48). Subgroup analyses based on the characteristics of the studies were conducted, and the association between DM and PD was significant in studies conducted in Asia (RR=1.30, 95% CI=1.01~1.69) and Europe (RR=1.45, 95% CI=1.09~1.94), and for patients with DM durations less than ten years (RR=1.31, 95% CI=1.27~1.37) and stroke (RR=1.16, 95% CI=1.03~1.31). Each study included in the analysis had methodologically good quality and showed no evidence of publication bias. Conclusion: DM resulted in a significantly increased risk of PD; therefore, prevention and early detection of PD in patients with DM should be encouraged.
목차
INTRODUCTION
RESULTS
DISCUSSION
CONCLUSION
REFERENCES
참고문헌 (34)
참고문헌 신청
American Diabetes Association / 2014 / Diagnosis and classification of diabetes mellitus / Diabetes Care 37(Suppl 1):S81~S90
Atsmon-Raz Y / 2015 / Co-aggregation of alpha-synuclein with amylin(HIAPP)leads to an increased risk in type II diabetes patients for developing Parkinson's disease / Biophysical Journal 108(2):524
Parkinson's Foundation / Understanding Parkinson's
Korean Statistical Information Service / Status of elderly diseases among applicants under 65 years of age by city and province
Camargo Maluf F / 2019 / Analysis of the relationship between type II diabetes mellitus and Parkinson's disease: a systematic review / Parkinson's Disease :4951379
Atsmon-Raz Y / 2015 / Co-aggregation of alpha-synuclein with amylin(HIAPP)leads to an increased risk in type II diabetes patients for developing Parkinson's disease / Biophysical Journal 108(2):524
Parkinson's Foundation / Understanding Parkinson's
Korean Statistical Information Service / Status of elderly diseases among applicants under 65 years of age by city and province
Camargo Maluf F / 2019 / Analysis of the relationship between type II diabetes mellitus and Parkinson's disease: a systematic review / Parkinson's Disease :4951379
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