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Trajectories of Depression and Their Associations with Mortality in Older People in Korea over 12 Years
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12년 이상의 기간 동안 우울 궤적과 한국 노인 사망률과의 연관성

논문 기본 정보

Type
Academic journal
Author
Sinhyung Lee (원광대학교 의과대학 원광대학교 산본병원 가정의학과) Hyeon Ho Choi (원광대학교 의과대학 원광대학교 산본병원 가정의학과) Seung Hee Kim (원광대학교 의과대학 원광대학교 산본병원 가정의학과) Jungun Lee (원광대학교병원 가정의학과)
Journal
대한임상건강증진학회 Korean Journal of Health Promotion Korean Journal of Health Promotion 제21권 제2호 KCI Accredited Journals
Published
2021.1
Pages
45 - 55 (11page)

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Trajectories of Depression and Their Associations with Mortality in Older People in Korea over 12 Years
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Background: As the course of depression and depressive symptoms over a lifetime varies between individuals, we used trajectory models based on the Korean Longitudinal Study of Aging to repeatedly measure symptoms over a follow-up period of 12 years to reveal the association with mortality. Methods: Three thousand five hundred sixty-one (1,483 men and 2,078 women) subjects aged over 65 years were included. Using the 10-item Center for Epidemiological Studies Depression Scale (CES-D 10), a tra jectory model was classified into different depressive symptom groups by gender. Cox proportional hazards models were used to investigate the association between depression trajectory and all-cause mortality. Results: We identified four trajectories of depressive symptoms in both men and women characterized by low CES-D 10 scores throughout the study: Low trajectory (LT), Moderate high trajectory (MHT), High, but increas ing trajectory (HIT), and High, but decreasing trajectory (HDT). The adjusted hazard ratios of the HIT, HDT, and MHT compared with LT in men were 2.12 (95% confidence interval [CI], 1.43-3.16), 1.52 (95% CI, 0.96-2.40), and 1.58 (95% CI, 1.10-2.26), respectively. In women, ratios of each group were 1.62 (95% CI, 1.25-2.10), 0.84 (95% CI, 0.61-1.16), and 1.20 (95% CI, 0.99-1.46). Conclusions: Highly depressive symptoms that increased over the 12 years period were associated with the highest risk of mortality in the Korean elderly population. The trajectory group with remitting depressive symp toms (HDT), despite having a similar baseline level of mood symptoms as the high increasing group (HIT) expe rienced a lower mortality risk in both men and women.
#우울증 #사망률 #노인 #한국인

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